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富马酸伏诺拉生联合莫沙必利治疗反流性食管炎的效果

喻金波 李中华 魏丽花

中国医学创新2025,Vol.22Issue(11):99-103,5.
中国医学创新2025,Vol.22Issue(11):99-103,5.DOI:10.3969/j.issn.1674-4985.2025.11.022

富马酸伏诺拉生联合莫沙必利治疗反流性食管炎的效果

Effect of Vonoprazan Fumarate Combined with Mosapride in Treatment of Reflux Esophagitis

喻金波 1李中华 2魏丽花1

作者信息

  • 1. 上饶市人民医院药剂科 江西 上饶 334000
  • 2. 上饶市人民医院消化内科 江西 上饶 334000
  • 折叠

摘要

Abstract

Objective:To observe the effect of Vonoprazan Fumarate combined with Mosapride in the treatment of reflux esophagitis.Method:According to the random number table method,80 patients with reflux esophagitis admitted to Shangrao People's Hospital from January 2023 to April 2024 were divided into two groups,with 40 cases each.The control group was treated with Vonoprazan Fumarate,and the observation group was treated with Mosapride on the basis of control group.The clinical efficacy,adverse reactions,laboratory indexes and disease indexes before and after treatment were compared between the two groups.Result:After treatment,gastrointestinal hormones,inflammatory factors and disease indicators in the observation group were better than those in the control group,with statistical significance(P<0.05).After treatment,the total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Vonoprazan Fumarate combined with Mosapride has a good effect in the treatment of reflux esophagitis,which can regulate laboratory indexes,relieve clinical symptoms,promote body rehabilitation,reduce the level of inflammatory factors and regulate the level of gastrointestinal hormones.

关键词

富马酸伏诺拉生/莫沙必利/反流性食管炎/不良反应

Key words

Vonoprazan Fumarate/Mosapride/Reflux esophagitis/Adverse reaction

引用本文复制引用

喻金波,李中华,魏丽花..富马酸伏诺拉生联合莫沙必利治疗反流性食管炎的效果[J].中国医学创新,2025,22(11):99-103,5.

中国医学创新

1674-4985

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