中国医学创新2025,Vol.22Issue(12):13-16,4.DOI:10.3969/j.issn.1674-4985.2025.12.004
度拉糖肽对2型糖尿病合并肝硬化患者血糖水平、肝硬化指标的影响
Effects of Dulaglutide on Blood Glucose Levels and Liver Cirrhosis Indexes in Patients with Type 2 Diabetes Mellitus Complicated with Liver Cirrhosis
摘要
Abstract
Objective:To analyze the effects of Dulaglutide on blood glucose and liver cirrhosis indexes in patients with type 2 diabetes mellitus.Method:A total of 80 patients with type 2 diabetes mellitus complicated with liver cirrhosis admitted to Ganzhou Fifth People's Hospital from January to December 2022 were selected as the study objects,and they were divided into control group and observation group by random drawing method,with 40 cases in each group.The control group was treated with insulin,and the observation group was treated with Dulaglutide on the basis of the control group.Blood glucose and liver cirrhosis index were compared between the two groups.Result:On the 30th,90th and 180th days of treatment and 1 year after treatment,the fasting blood glucose(FBG)and 2 h postprandial blood glucose(2 h PBG)levels in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).On the 180th days of treatment and 1 year after treatment,the liver stiffness measurement(LSM)of the observation group were lower than those of the control group,the differences were statistically significant(P<0.05).Conclusion:Dulaglutide can improve blood glucose levels and liver function in patients with type 2 diabetes mellitus complicated with liver cirrhosis.关键词
度拉糖肽/2型糖尿病/肝硬化/血糖/肝硬度值Key words
Dulaglutide/Type 2 diabetes mellitus/Liver cirrhosis/Blood glucose/Liver stiffness measurement引用本文复制引用
袁芝娴,赖龙斌,陈申,邓鹏,黄颖..度拉糖肽对2型糖尿病合并肝硬化患者血糖水平、肝硬化指标的影响[J].中国医学创新,2025,22(12):13-16,4.基金项目
江西省卫生健康委科技计划项目(202511103) (202511103)