中国医学创新2025，Vol.22Issue(12)：17-20,4.DOI:10.3969/j.issn.1674-4985.2025.12.005
参麦注射液联合AG化疗方案对晚期不可切除胰腺癌患者肿瘤标志物及免疫功能的影响
Effects of Shenmai Injection Combined with AG Chemotherapy Regimen on Tumor Markers and Immune Function in Patients with Advanced Unresectable Pancreatic Cancer
田宁 1张山燕 1周远 1王娟1
作者信息
- 1. 泰安市肿瘤防治院化疗科 山东 泰安 271000
- 折叠
摘要
Abstract
Objective:To explore the effects of Shenmai Injection combined with AG chemotherapy regimen on tumor markers and immune function in patients with advanced unresectable pancreatic cancer.Method:The clinical data of 80 patients with advanced unresectable pancreatic cancer admitted to Tai'an Tumour Prevention and Treatment Hospital from January 2021 to June 2023 were retrospectively analyzed,and they were divided into observation group and control group according to different treatment regimens,with 40 cases in each group.The control group was treated with AG chemotherapy regimen,and the observation group was treated with Shenmai Injection on the basis of control group.Tumor markers,immune function and clinical efficacy were compared between the two groups.Result:After treatment,the levels of carcinoembryonic antigen(CEA)and carbohydrate antigen 19-9(CA19-9)in both groups were decreased,and those in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of CD3+and CD4+in both groups were increased,and those in the observation group were higher than those in the control group,the levels of CD8+in both groups were decreased,and that in the observation group was lower than that in the control group(P<0.05).There were no significant differences in objective response rate(ORR),disease control rate(DCR)and mortality between the two groups(P>0.05).Conclusion:Shenmai Injection combined with AG chemotherapy regimen in patients with advanced unresectable pancreatic cancer can reduce the levels of tumor markers,improve the immune function of patients.关键词
参麦注射液/AG化疗方案/胰腺癌/肿瘤标志物/免疫功能Key words
Shenmai Injection/AG chemotherapy regimen/Pancreatic cancer/Tumor markers/Immune function引用本文复制引用
田宁,张山燕,周远,王娟..参麦注射液联合AG化疗方案对晚期不可切除胰腺癌患者肿瘤标志物及免疫功能的影响[J].中国医学创新,2025,22(12):17-20,4.
