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华蟾素胶囊联合富马酸替诺福韦二吡呋酯对肝癌患者肝功能的改善效果

朱慧婷 李梦琳 邬飞源

中国医学创新2025,Vol.22Issue(12):69-73,5.
中国医学创新2025,Vol.22Issue(12):69-73,5.DOI:10.3969/j.issn.1674-4985.2025.12.017

华蟾素胶囊联合富马酸替诺福韦二吡呋酯对肝癌患者肝功能的改善效果

Improvement Effect of Huachansu Capsules Combined with Tenofovir Disoproxil Fumarate on Liver Function in Patients with Liver Cancer

朱慧婷 1李梦琳 1邬飞源1

作者信息

  • 1. 萍乡市第二人民医院药剂科 江西 萍乡 337000
  • 折叠

摘要

Abstract

Objective:To explore the effect of Huachansu Capsules combined with Tenofovir Disoproxil Fumarate on patients with liver cancer.Method:A total of 84 patients with liver cancer admitted to Pingxiang Second People's Hospital from January 2021 to January 2024 were selected and divided into two groups according to random number table method,with 42 patients in each group.The control group was treated with Tenofovir Disoproxil Fumarate,and the observation group was treated with Huachansu Capsules on the basis of the control group.The clinical efficacy,hepatitis B virus gene(HBV-DNA),liver function indexes[alanine aminotransferase(ALT),aspartate aminotransferase(AST),glutamyltransferase(GGT)]and the occurrence of adverse reactions between the two groups were compared.Result:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the HBV-DNA level in the observation group was lower than that in the control group,the scores of liver pain,fatigue,low eating and liver enlargement were lower than those in the control group,and the levels of ALT,AST and GGT were lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Huachansu Capsules combined with Tenofovir Disoproxil Fumarate has a good effect in the treatment of liver cancer patients,which can not only alleviate clinical symptoms,promote the improvement of liver function,reduce the level of HBV-DNA,and do not increase adverse reactions.

关键词

肝癌/华蟾素胶囊/富马酸替诺福韦二吡呋酯/肝功能/乙型肝炎病毒基因/不良反应

Key words

Liver cancer/Huachansu Capsules/Tenofovir Disoproxil Fumarate/Liver function/Hepatitis B virus gene/Adverse reactions

引用本文复制引用

朱慧婷,李梦琳,邬飞源..华蟾素胶囊联合富马酸替诺福韦二吡呋酯对肝癌患者肝功能的改善效果[J].中国医学创新,2025,22(12):69-73,5.

中国医学创新

1674-4985

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