中国医学创新2025，Vol.22Issue(12)：154-158,5.DOI:10.3969/j.issn.1674-4985.2025.12.037
吡柔比星染色定位在非肌层浸润性膀胱癌手术治疗中的应用
Application of Pirarubicin Staining Localization in the Surgical Treatment of Non-muscle-invasive Bladder Cancer
陈秀祥 1刘宇 1徐建1
作者信息
- 1. 毕节市中医医院泌尿外科 贵州 毕节 551700
- 折叠
摘要
Abstract
Objective:To analyze the application effect of Pirarubicin(THP)staining localization in the surgical treatment of non-muscle-invasive bladder cancer(NMIBC).Method:The clinical data of 83 NMIBC patients admitted to the Department of Urology,Bijie Traditional Chinese Medicine Hospital from January 2022 to July 2023 were retrospectively analyzed.They were divided into two groups according to different treatment methods.The control group(n=40)was treated with transurethral resection of bladder tumor,and the observation group(n=43)underwent THP staining localization by irrigation of bladder 30 min before surgery,and then transurethral resection of bladder tumor was performed.The operation status,tumor markers levels,secretory regulatory factors levels,tumor recurrence and progression were compared between the two groups.Result:There were no significant differences in operation time,intraoperative blood loss and postoperative hospital stay between the two groups(P>0.05).The levels of tumor markers and secretory regulatory factors in the observation group 4 weeks after surgery were lower than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in the incidence of postoperative complications and the rate of tumor progression between the two groups(P>0.05).The recurrence rate of tumor in the observation group was 4.65%,which was lower than 25.00%in the control group,the difference was statistically significant(P<0.05).Conclusion:THP staining localization before transurethral resection of bladder tumor in NMIBC patients can reduce the levels of tumor markers and tumor recurrence rate.关键词
经尿道膀胱肿瘤电切术/吡柔比星/非肌层浸润性膀胱癌Key words
Transurethral resection of bladder tumor/Pirarubicin/Non-muscle-invasive bladder cancer引用本文复制引用
陈秀祥,刘宇,徐建..吡柔比星染色定位在非肌层浸润性膀胱癌手术治疗中的应用[J].中国医学创新,2025,22(12):154-158,5.
