中国医学创新2025，Vol.22Issue(12)：180-184,5.DOI:10.3969/j.issn.1674-4985.2025.12.043
基于"脾肾阳虚,痰浊阻滞"理论探讨神经根型颈椎病与线粒体自噬的关系
Exploring the Relationship between Cervical Spondylotic Radiculopathy and Mitophagy Based on the Theory of"Yang Deficiency of Spleen and Kidney,Blockade of Phlegm-Turbidity"
摘要
Abstract
The pathogenesis and treatment of cervical spondylotic radiculopathy are the focus of medical research at present.Mitophagy is the process of removing or degrading damaged and aged mitochondrion.Mitophagy plays an important role in the occurrence and development of intervertebral disc degenerative change and neuropathic pain,and both intervertebral disc degenerative change and neuropathic pain are closely related to cervical spondylotic radiculopathy,so it is inferred that mitophagy is closely related to the onset of cervical spondylotic radiculopathy.According to traditional Chinese medicine,the main pathogenesis of cervical spondylotic radiculopathy is yang deficiency of spleen and kidney and blockade of phlegm-turbidity,which is similar to mitophagy at the microscopic level.Therefore,based on the theory of"Yang deficiency of spleen and kidney,blockade of phlegm-turbidity",this paper will explore the relationship between mitophagy and cervical spondylotic radiculopathy from the perspective of traditional Chinese medicine and western medicine,providing a new direction and target for the research and treatment of cervical spondylotic radiculopathy.关键词
神经根型颈椎病/脾肾阳虚/痰浊阻滞/线粒体自噬Key words
Cervical spondylotic radiculopathy/Yang deficiency of spleen and kidney/Blockade of phlegm-turbidity/Mitophagy引用本文复制引用
王悦,董平,姚广源,胡凯..基于"脾肾阳虚,痰浊阻滞"理论探讨神经根型颈椎病与线粒体自噬的关系[J].中国医学创新,2025,22(12):180-184,5.基金项目
内蒙古自治区自然科学基金项目(2022QN08010) （2022QN08010）
内蒙古自治区卫生健康科技计划项目(202201193) （202201193）
