摘要
Abstract
Objective:To explore the assessment value of 3.0T magnetic resonance(MR)diffusion weighted imaging(DWI)-apparent diffusion coefficient(ADC)on disease severity in elderly patients with acute pancreatitis(AP).Methods:A total of 68 elderly AP patients who admitted to Weihai Hospital of Traditional Chinese Medicine from August 2023 to September 2024 were retrospectively selected,and they were enrolled in cases group,and 40 healthy persons were included in healthy control group.According to the disease severity,the cases group were divided further into mild-moderate group(n=35)and severe group(n=33).The ADC value and fast diffusion ADC(Ft ADC)fraction of all groups were compared,and receiver operating characteristic(ROC)curve was adopted to evaluate the predictive value of ADC value on the disease severity of AP patients.Results:There were significant differences in ADC values and Ft ADC values among healthy control group,mild-moderate group and severe group(F=30.821,23.145,P＜0.05).The orders of ADC values were as follows from high to low:severe group(0.92±0.24)＞mild-moderate group(0.86±0.23)＞control group(0.58±0.12).The orders of Ft ADC values were as follows from high to low:healthy control group(0.59±0.18)＞mild-moderate group(0.45±0.15)＞severe group(0.35±0.11).The accuracy,sensitivity and specificity of ADC value combined with Ft ADC value were respectively 93.33%,96.23%and 90.38%in diagnosing disease severity.The accuracy and sensitivity of the combined examination were respectively higher than 82.86%and 75.47%of single ADC value,and were respectively higher than 85.71%and 84.91%of single Ft ADC value.Conclusion:With the increasing of disease severity of acute pancreatitis,ADC value gradually decreased,while Ft ADC value gradually increased.The diagnostic efficiency of the combination of ADC value and Ft ADC value for the disease severity were significantly higher than that of single indicator.Therefore,the combined application of ADC value and Ft ADC can help to improve the assessment accuracy for the disease severity of elderly AP patients,which can provide important basis for clinical treatment and disease management.关键词
磁共振(MR)/弥散加权成像(DWI)/表观弥散系数(ADC)值/老年急性胰腺炎/疾病严重程度Key words
Magnetic resonance(MR)/Diffusion weighted imaging(DWI)/Apparent dispersion coefficient(ADC)value/Senile acute pancreatitis/Disease severity分类
医药卫生
