肿瘤防治研究2025，Vol.52Issue(4)：251-255,5.DOI:10.3971/j.issn.1000-8578.2025.24.1329
河南省林县食管癌高发现场防治传承研究的历史、经验、机遇和挑战
History,Experience,Opportunities,and Challenges in Esophageal Cancer Prevention and Treatment in Linxian,Henan Province,A High Incidence Area for Esophageal Cancer
摘要
Abstract
Linxian County in Henan Province,Northern China is known as the region with the highest incidence and mortality rate of esoph-ageal cancer worldwide.Since 1959,the Henan medical team has conducted field work on esophageal cancer prevention and treatment in Linxian.Through three generations of effort exerted by oncol-ogists over 65 years of research on eso-phageal cancer prevention and treatment in Linxian,the incidence rate of esop-hageal squamous cell carcinoma in this area has dropped by nearly 50%,and the 5-year survival rate has increased to 40%,reaching the international leading level.This article aims to summarize the history,present opportunities and new challenges,and explore the experience of esophageal cancer prevention and treatment in Linxian(referred to as the"Linxian experience"),providing reference and guidance to cancer prevention and treatment research in China.关键词
食管癌/林县经验/现场防治研究/食管癌高发区Key words
Esophageal cancer/Linxian experience/Field-study on prevention and treatment/High incidence area for esophageal cancer分类
临床医学引用本文复制引用
王立东,王苒,鲍启德,纪爱芳,马磊,高社干,张晓倩,宋昕,赵学科,尤朵,雷玲玲,徐瑞华,黄金,韩文莉..河南省林县食管癌高发现场防治传承研究的历史、经验、机遇和挑战[J].肿瘤防治研究,2025,52(4):251-255,5.基金项目
国家科技重大专项(2024ZD0520900,2024ZD0520906) （2024ZD0520900,2024ZD0520906）
国家科技部国家重点研发计划"精准医学研究"重点专项(2016YFC0901403) National Science and Technology Major Project(No.2024ZD0520900,No.2024ZD0520906) （2016YFC0901403）
National Key Res-earch and Development Program of China"Precision Medicine Research"Key Special Project(No.2016YFC0901403) （No.2016YFC0901403）
