肿瘤防治研究2025，Vol.52Issue(4)：297-304,8.DOI:10.3971/j.issn.1000-8578.2025.24.0959
基于CiteSpace及VOSviewer的肿瘤治疗领域研究热点与趋势的可视化分析
Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer
摘要
Abstract
Objective To explore the research hotspots and development trends in the field of cancer treatment in the past decade.Methods The CNKI and Web of Science Core Collection databases were searched for Chinese and English articles related to cancer treatment published over the last 10 years.Bibliometric research methods were employed,including keyword cluster analysis of published literature.Results A total of 45 455 Chinese articles and 866 958 English articles were retrieved.Combining the visualization analysis results and the current research dilemma of tumor treatment revealed that the current research hotspots of tumor treatment domestically and internationally can primarily focus on four key areas.In the realm of targeted therapy,efforts are directed towards the discovery of new drug targets,overcoming resistance to targeted therapy,and the development of monoclonal antibodies and antibody-drug conjugates.In the field of immunotherapy,the emphasis lies in enhancing the response rate to immune checkpoint inhibitors,determining the mechanisms behind resistance to immunotherapy,and improving the safety of treatment.The research in traditional Chinese medicine(TCM)covers evidence-based evaluation studies on TCM treatment,the identification of populations that can gain the most benefit from TCM,and strategies for improving the quality of life.In the area of novel drug development,cutting-edge technologies,such as organoid-based screening for anticancer drugs,synthetic biology,and artificial intelligence,are under investigation.Conclusion New targeted drugs,immune efficacy improvement,multidisciplinary integ-ration,nano-delivery,and TCM innovation are the key research directions in the field of tumor therapy in the future.关键词
肿瘤治疗/靶向治疗/免疫治疗/中医药治疗/新药研发/文献计量学Key words
Tumor therapy/Targeted therapy/Immunotherapy/Traditional Chinese medicine therapy/New drug development and research/Bibliometrics分类
临床医学引用本文复制引用
方宇航,张楚楚,隋白鹭,王妍,王润兮,陈宇,袁欣禾,杨洪军,张英..基于CiteSpace及VOSviewer的肿瘤治疗领域研究热点与趋势的可视化分析[J].肿瘤防治研究,2025,52(4):297-304,8.基金项目
China Academy of Chinese Medical Sciences Soft Science Special Project-Strategic Research on Technological Breakthroughs in Traditional Chinese Medicine for the Prevention and Treatment of Major Chronic Diseases(No.ZZ17-RKX-01) 中国中医科学院软科学专项-中医药防治重大慢性疾病科技攻关战略研究(ZZ17-RKX-01) （No.ZZ17-RKX-01）
