中国现代中药2025，Vol.27Issue(4)：738-741,4.DOI:10.13313/j.issn.1673-4890.20240909002
延胡索提取液在大孔吸附树脂柱分离中吸附过程研究
Adsorption Process of Corydalis Rhizoma Extract in the Column Separation by Macroporous Adsorbent Resin
摘要
Abstract
Objective:To investigate the kinetics of Corydalis Rhizoma extract passing through macroporous adsorbent resin,analyze the adsorption pattern,and select a suitable model for simulating the adsorption process.Methods:The kinetics of the adsorption process was simulated by the Langmuir isothermal adsorption model with dehydrocorydaline as the measurement index.A fixed-bed adsorption test was carried out and the integrated rate model was used to simulate the adsorption kinetics.Results:The Langmuir model effectively simulated the isothermal adsorption process of Corydalis Rhizoma extract in macroporous adsorbent resin at 298-308 K.The integrated rate model accurately simulated the fixed-bed adsorption process of the extract by minimizing the mean square error(MSE)between the penetration curve and the simulated value by the least squares fitting method.Conclusion:The penetration curve analysis of Corydalis Rhizoma extract passing through the macroporous adsorbent resin column helps to infer the mass transfer coefficient in adsorption,providing a basis for the production,separation,and purification of Corydalis Rhizoma extract.关键词
延胡索/吸附/脱氢紫堇碱/穿透曲线/模型拟合Key words
Corydalis Rhizoma/adsorption/dehydrocorydaline/penetration curve/model fitting分类
中医学引用本文复制引用
范嘉俊,刘光宇,张鹏,刘建勋..延胡索提取液在大孔吸附树脂柱分离中吸附过程研究[J].中国现代中药,2025,27(4):738-741,4.基金项目
中国中医科学院科技创新工程项目(CI2021A04403) （CI2021A04403）
