国际医药卫生导报2025，Vol.31Issue(8)：前插2,1234-1239,7.DOI:10.3760/cma.j.cn441417-20241101-08001
基于超声弹性成像和MRI构建早期乳腺癌介入消融效果的预测模型
Prediction model of effect of interventional ablation for early breast cancer based on ultrasonic elastography and MRI
摘要
Abstract
Objective To explore the prediction model of the effect of interventional ablation for early breast cancer based on magnetic resonance imaging(MRI)and ultrasonic elastography.Methods Retrospective analysis was made on 126 female patients with breast cancer admitted to First Affiliated Hospital of Xi'an Medical University from January 2021 to January 2024.They were(49.46±5.17)years old.All the patients were treated with ultrasound guided radiofrequency ablation.Six months after the surgery,the patients were divided into a pathological complete remission(pCR)group and a non-pCR group according to the pathological results.The ultrasonic elastic imaging indicator[shear wave velocity(SWV)]and MRI indicators[T1 weighted(T1WI)signal,T2W1 low fat suppression signal,enhanced signal,and apparent diffusion coefficient(ADC)]were compared between the two groups.The influencing factors of the effect of interventional ablation for early breast cancer were analyzed to build a prediction model for evaluating the effect of interventional ablation for early breast cancer.The data were compared between the two groups by t and x2 tests.The influencing factors were analyzed by the logistic regression model.The fitting degree was evaluated by the Hosmer-Lemeshow test.The predictive efficacy was evaluated by the receiver operating characteristic curve(ROC).Results Among the 126 patients,114 had pCR,and 12 had non-pCR.The maximum tumor diameter,SWV ratio of diseased side to opposite side(SWVr),T1WI low/equal signal,T2WI fat suppression high signal,and enhanced signal were the risk factors of non-pCR in interventional ablation for early breast cancer,and ADC was the protective factor(all P＜0.05).The sensitivity,specificity,and area under the curve of the nomogram model for predicting non-pCR in interventional ablation for early breast cancer were 0.862,0.874,and 0.879,respectively.Conclusion Maximum tumor diameter,SWVr,T1WI signal,T2WI low fat suppression signal,enhanced signal,and ADC can evaluate the effect of interventional ablation for early breast cancer,and building a prediction model is helpful to identify the effect of interventional ablation for early breast cancer.关键词
乳腺癌/早期/消融/超声弹性成像/磁共振成像/预测模型Key words
Breast cancer/Early stage/Ablation/Ultrasonic elastography/Magnetic resonance imaging/Predictive model引用本文复制引用
罗婷,严婷,何蕊..基于超声弹性成像和MRI构建早期乳腺癌介入消融效果的预测模型[J].国际医药卫生导报,2025,31(8):前插2,1234-1239,7.基金项目
陕西省自然科学基础研究计划(2020JQ-554) Basic Research Plan of Natural Science in Shaanxi(2020JQ-554) （2020JQ-554）
