摘要
Abstract
Objective:To observe the efficacy of Xiaoqinglong decoction combined with conventional western medicine in treating bronchial asthma and its impact on serum levels of surfactant protein D(SP-D)and transforming growth factor-β1(TGF-β1).Methods:98 patients with bronchial asthma were divided into two groups according to ran-dom number table,with 49 cases in each group.Those in the observation group were treated with Xiaoqinglong decoc-tion combined with conventional western medicine,meanwhile those in the control group were only administrated with conventional western medicine.Both groups were treated for 1 month.Before and after treatment,the clinical efficacy,changes in serum SP-D and TGF-β1 levels,traditional Chinese medicine(TCM)syndrome scores,pulmonary function indices,asthma control test(ACT)scores,and marks asthma quality of life questionnaire(Marks-AQLQ)scores were compared between the two groups.Result:The total effective rate of the observation group was 93.88%,and that of the control group was 79.59%,with a significant difference between these two groups(P＜0.05).Comparing to those before treatment,TCM syndrome scores,Marks-AQLQ scores,and serum SP-D and TGF-β1 levels in both groups were low-er,while the pulmonary function indices and ACT scores were higher(P＜0.05).The observation group exhibited sig-nificantly greater improvements in these indicators compared to the control group(P＜0.05).Conclusion:Xiaoqinglong decoction combined with conventional western medicine enhances the clinical efficacy in bronchial asthma patients by effectively alleviating clinical symptoms,improving pulmonary function,regulating serum SP-D and TGF-β1 levels,and thereby improving the patients'quality of life.关键词
支气管哮喘/小青龙汤/长效β受体激动剂/血清表面活性蛋白D/转化生长因子-β1Key words
bronchial asthma/Xiaoqinglong decoction/long-acting β-receptor agonist/surfactant protein D/trans-forming growth factor-β1分类
医药卫生
