高等学校化学学报2025，Vol.46Issue(5)：47-53,7.DOI:10.7503/cjcu20250033
葫芦[n]脲主客体作用介导光可移除保护基团分子的光解反应
Photolysis of Photoremovable Protecting Group Molecule Mediated by the Host-guest Interaction of Cucurbit[n]uril
摘要
Abstract
An aromatic acridine derivative with photoremovable protecting group(PPG)properties was designed and synthesized.The host-guest recognition process between this guest molecule and cucurbit[n]uril(CB[n],n=7,8,10)was investigated,along with the effects of host-guest interaction on the photolysis of the guest in aqueous-phase using nuclear magnetic resonance(NMR),ultraviolet visible(UV-Vis)and fluorescence spectroscopies.The results showed that CB[7]formed a 1׃1 host-guest inclusion complex,while CB[8]formed both 1׃1 and 1׃2 complexes with the guest.Similarly,CB[10]exhibited a 1׃2 binding mode.Furthermore,CB[7]was found to inhibit the photolysis,whereas CB[8]significantly enhanced the photolysis rate of the guest.This study highlights how subtle variations in CB[n]cavity size influence the photolysis reaction,offering insights into the design of CB[n]-based nanoreactor-mediated supramolecular systems for aqueous-phase photolysis of PPG molecules.关键词
光可移除保护基团/光解反应/主客体作用/葫芦[n]脲/纳米反应器Key words
Photoremovable protecting group/Photolysis reaction/Host-guest interaction/Cucurbit[n]uril/Nanoreactor分类
化学引用本文复制引用
刘冲,刘思敏..葫芦[n]脲主客体作用介导光可移除保护基团分子的光解反应[J].高等学校化学学报,2025,46(5):47-53,7.基金项目
国家自然科学基金(批准号:21871216)资助. Supported by the National Natural Science Foundation of China(No.21871216). （批准号:21871216）
