口腔疾病防治2025，Vol.33Issue(5)：377-384,8.DOI:10.12016/j.issn.2096-1456.202440479
灼口综合征患者睡眠质量特点及其影响因素初步分析
Characteristics of sleep quality and influencing factors in patients with burning mouth syndrome:a prelimi-nary analysis
摘要
Abstract
Objective To investigate the sleep quality in patients with burning mouth syndrome(BMS)and its influ-encing factors,providing a basis for developing sleep intervention measures to reduce the impact of BMS symptoms.Methods This study was reviewed and approved by the Medical Ethics Committee,and informed consent was obtained from patients.A total of 150 patients with BMS and 150 healthy volunteers were enrolled as subjects in this study.The Pittsburgh sleep quality index(PSQI)was used to assess the sleep quality of patients with BMS.Visual analog scale(VAS)was used to assess the degree of oral mucosal pain,generalized anxiety disorder 7-item scale(GAD-7)was used to assess the frequency of anxiety symptoms,and the patient health questionnaire depression questionnaire(PHQ-9)was used to assess the frequency of depression symptoms.Univariate analysis was performed to identify potential influencing factors affecting sleep quality in patients with BMS,and multiple linear regression analysis was employed to determine independent risk factors.Results The PSQI score for patients with BMS was 7.61±4.29,which was significantly high-er than that of healthy controls(P=0.016).In the PSQI subscale analysis,patients with BMS exhibited increased sleep latency,decreased sleep duration,and lower sleep efficiency compared to healthy controls(P＜0.05).Patients with BMS and comorbid sleep difficulties had significantly higher scores on GAD-7 and PHQ-9 compared to the patients with BMS without sleep difficulties(P＜0.001),but there was no significant difference in pain VAS scores between the two(P=0.068).Multiple linear regression analysis revealed that longer disease duration(＞6 months),the presence of systemic concom-itant symptoms(such as headache and mental stress),and higher depression scores were identified as independent risk factors affecting sleep quality in patients with BMS.Conclusion For patients with BMS,long course of illness,presence of headaches,high mental stress,and depressive symptoms may be independent factors affecting their sleep quality.关键词
灼口综合征/睡眠质量/睡眠困难/烧灼感/负性情绪/焦虑症状/抑郁症状/影响因素Key words
burning mouth syndrome/sleep quality/sleep difficulties/burning sensation/emotional distur-bance/anxiety symptoms/depressive symptoms/influencing factors分类
口腔医学引用本文复制引用
卢成辉,杨成龙,周璇,江新香,唐国瑶..灼口综合征患者睡眠质量特点及其影响因素初步分析[J].口腔疾病防治,2025,33(5):377-384,8.基金项目
上海卫健委临床科研资助项目(202040458) （202040458）
上海交通大学医学院附属新华医院"学科攀峰计划"建设项目(XKPF2024B500) This study was supported by the Clinical Research Funding,Shanghai Municipal Health Commission(No.202040458)and the grants from the Construction Project of the"Discipline Peak-Climbing Plan"of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(No.XKPF2024B500). （XKPF2024B500）
