国际妇产科学杂志2025，Vol.52Issue(2)：217-221,5.DOI:10.12280/gjfckx.20240977
锌与多囊卵巢综合征的关系
Relationship between Zinc and Polycystic Ovary Syndrome
摘要
Abstract
Polycystic ovary syndrome(PCOS)is a heterogeneous endocrine disorder mainly characterized by polycystic ovarian changes,insulin resistance,and hyperandrogenism,which seriously affects women's physical and mental health.However,its pathogenesis is still unclear and treatment options are limited.Oxidative stress is an important factor affecting the pathogenesis of PCOS and is closely related to insulin resistance,hyperandrogenemia,and chronic inflammation.Zinc is an essential nutrient with powerful antioxidant and anti-inflammatory properties.Metabolically,zinc is also involved in the synthesis and storage of insulin and regulating insulin-related pathways.Clinical studies have shown that patients with PCOS exhibit lower serum zinc levels compared to non-PCOS populations and that micronutrient zinc supplementation improves oxidative stress,insulin resistance,and hyperandrogenism in PCOS patients.The correlation between zinc and metabolic dysfunction and oxidative stress in PCOS is summarized,to provide a reference for the preventive management and treatment of PCOS.关键词
锌/多囊卵巢综合征/胰岛素抵抗/氧化性应激/雄激素增多症Key words
Zinc/Polycystic ovary syndrome/Insulin resistance/Oxidative stress/Hyperandrogenism引用本文复制引用
徐淑颖,徐海鹏,王丽娜,张阳..锌与多囊卵巢综合征的关系[J].国际妇产科学杂志,2025,52(2):217-221,5.基金项目
沈阳市科学技术计划项目-公共卫生研发专项(22-321-33-41) （22-321-33-41）
辽宁省教育厅2022年度高等学校基本科研项目(LJKZZ20220107) （LJKZZ20220107）
辽宁省科技计划联合计划(应用基础研究项目)(2023JH2/101700220) （应用基础研究项目）
