黑龙江八一农垦大学学报2025，Vol.37Issue(2)：40-45,6.DOI:10.3969/j.issn.1002-2090.2025.02.006
围产期酮病奶牛血液能量代谢指标特征的分析
Characteristics of Blood Energy Metabolism in Dairy Cows with Ketosis During Perinatal Period
摘要
Abstract
Thirty-five pregnant cows were randomly selected and plasma samples were collected at 21 d before delivery,on the day of delivery,and 3,7,14,21 and 28 d after delivery.The ketosis group was treated with plasma β-hydroxybutyrate(BHBA)≥1.2 mmol·L-1 at any time point,and the control group was treated with BHBA<1.2 mmol·L-1.As result,blood β-hydroxybutyric acid(BHBA)level increased to more than 1.2 mmol·L-1 after postpartum 3 days,which was higher than that of control cows.Compared with the control group,the levels of aspartate aminotransferase in blood at 7 days postpartum,and non-esterified fatty acids in blood at 3 d and 28 d postpartum were slightly higher.During the whole follow-up period,the levels of glutamyl transpeptidase and lactate dehydrogenase in blood were lower than those in control group,and the levels of alanine aminotransferase in blood from 14 to 7 days before delivery were lower than those in control group.The relationship between related hormone indexes and β-hydroxybutyric acid was analyzed by ROC curve.The specificity and sensitivity of fibroblast growth factor 15(FGF15)were not correlated with BHBA.Finally,it was established that glucagon-like peptide-1(GLP-1)and fibroblast growth differentiation factor 19(FGF-19)were positively correlated with β-hydroxybutyric acid(BHBA),and that PYY was negatively correlated with BHBA,so as to establish the early warning technology of ketosis.关键词
奶牛/酮病/血液生化指标/ROC回归曲线分析Key words
cow/ketosis/blood biochemical index/ROC regression curve analysis分类
畜牧业引用本文复制引用
邹存志,田艳,范文文,杨威,张冰冰,张旭..围产期酮病奶牛血液能量代谢指标特征的分析[J].黑龙江八一农垦大学学报,2025,37(2):40-45,6.基金项目
黑龙江地区犬冠状病毒分子流行病学调查及病毒分离与鉴定(C2017051). （C2017051）
