吉林中医药2025，Vol.45Issue(4)：484-490,7.DOI:10.13463/j.cnki.jlzyy.2025.04.025
基于炎症探讨针灸治疗抑郁机制的研究进展
Research progress of the mechanisms of acupuncture on treating depression through modulating inflammation
摘要
Abstract
Inflammation refers to the defense response of the human body to pathogen infection and tissue injuries.Appropriate inflammation helps remove pathogenic factors and enhance body's resistance,whereas pathological inflammation leads to damage in various tissue and organs.Acupuncture turns out to have definite efficacy in depression treatment,mediated by its regulation of inflammation to ameliorate depression.This article reviews the research conducted in the past five years on the mechanisms on regulating inflammation via acupuncture in the treatment of depression.It is found that acupuncture exerts anti-depression effects through the regulation of microglia,inflammasome,inflammatory mediators,the blood-brain barrier,and intestinal flora,thereby providing a clear idea for its follow-up mechanism research,and laying a theoretical foundation for the clinical application of acupuncture in this regard.关键词
针灸/抑郁/炎症/炎性小体/小胶质细胞Key words
acupuncture/depression/inflammation/inflammasome/microglia分类
医药卫生引用本文复制引用
杜睿博,马琳,刘征..基于炎症探讨针灸治疗抑郁机制的研究进展[J].吉林中医药,2025,45(4):484-490,7.基金项目
黑龙江省自然科学基金项目(LH2022H083) （LH2022H083）
黑龙江省中医药管理局国医大师学术思想传承科研课题(GY2022-06) （GY2022-06）
