集美大学学报（自然科学版）2025，Vol.30Issue(2)：121-127,7.DOI:10.19715/j.jmuzr.2025.02.03
老鼠簕乙醇提取物化学成分的提取、分离与鉴定
Extraction,Isolation and Identification of Chemical Constituents from Ethanol Extract of Acanthus ilicifolius
摘要
Abstract
In order to deeply study the chemical components of Acanthus ilicifolius,this study used silica column chromatography,Sephadex LH-20 column chromatography,and other means to separate and purify its chemical components.The separated monomer compounds of Acanthus ilicifolius which were determined by their physicochemical property and modern spectroscopic analysis including 1H-NMR,13C-NMR,and 2D NMR.Twelve compounds were isolated and their structures were identified as(2R)-2-O-β-D-glucopyranosyl-2H-l,4-benzox-azine-3(4H)-one(1),(2R)-2-hydroxy-2H-1,4-benzoxazine-3(4H)-one(2),(2S)-2-hydroxy-2H-1,4-benzoxazine-3(4H)-one(3),4-hydroxyl-2-benzoxazolinone(4),(2R)-7-chloro-2-O-β-D-glucopyranosyl-2H-l,4-benzoxazin-3(4H)-one(5),luteolin-7-O-β-D-glucuronopyranoside methyl ester(6),apigenin-7-O-β-D-glucuronopyranoside methyl ester(7),Ilicifolius acids A(8),adenine(9),(2S)-2-O-β-D-glucopyranosyl-2H-l,4-benzoxazin-3(4H)-one(10),acteoside(11),and isoacteoside(12).Compounds 6 and 9 were isolated from Acanthus ilicifolius for the first time.关键词
老鼠簕/化学成分/生物碱/黄酮/苯乙醇苷Key words
Acanthus ilicifolius/chemical constituents/alkaloid/flavonoid/phenylethanol glycoside分类
中医学引用本文复制引用
陈子然,高苏蕊,简敏如,刘韶松,李元跃..老鼠簕乙醇提取物化学成分的提取、分离与鉴定[J].集美大学学报（自然科学版）,2025,30(2):121-127,7.基金项目
福建省高校产学合作重大项目"滨海湿地生态修复技术红树林种植-养殖耦合系统的研发与示范"(2021Y4013) （2021Y4013）
厦门华侨亚热带植物引种园园设课题"红树植物老鼠簕提取物质量标准的初步研究"(2023-03) （2023-03）
