海洋科学2025，Vol.49Issue(1)：93-104,12.DOI:10.11759/hykx20240426002
氨基葡萄糖催化转化的5-羟甲基糠醛的稳定载药体的构建及对根结线虫的影响
Construction of a stable drug carrier for 5-hydroxymethyl-furfural catalytically transformed with glucosamine and its efficacy against root-knot nematodes
摘要
Abstract
5-Hydroxymethylfurfural(HMF)is a platform compound with broad prospects for application and sig-nificant in vitro nematocidal activity.However,its instability at room temperature has greatly limited its further development and usage.In this experiment,HMF was first synthesized using glucosamine,a monomer derived from chitin,with a yield of 42.1%.Subsequently,the layered clay mineral bentonite was employed as a carrier for load-ing HMF,which effectively improved its stability at room temperature.The nematicidal activity of this drug-carrying system was verified in pot experiments.Finally,the reasons for the stability obtained by the combi-nation of HMF and bentonite were preliminarily explained through a series of structural characterization techniques.Thus,the long-term storage stability of HMF at room temperature was realized,and the current methods of root-knot nematode control were expanded.关键词
5-羟甲基糠醛/氨基葡萄糖/生物质转化/膨润土/根结线虫Key words
5-Hydroxymethylfurfural/glucosamine/biomass conversion/bentonite/root-knot nematode分类
植物保护学引用本文复制引用
胡路杰,李鹏程,秦玉坤,王林松,范兆乾,高堃,周潞潇,王中玮,张琦璘,宋亚东,邢荣娥..氨基葡萄糖催化转化的5-羟甲基糠醛的稳定载药体的构建及对根结线虫的影响[J].海洋科学,2025,49(1):93-104,12.基金项目
国家自然科学基金(42076126)the National Natural Science Foundation of China,No.42076126 （42076126）
