华南农业大学学报2025，Vol.46Issue(3)：287-300,14.DOI:10.7671/j.issn.1001-411X.202405011
纳米药物递送系统在耐药病原菌防控中的研究进展
Advances of nano-drug delivery systems in the prevention and control of drug-resistant pathogenic bacteria
摘要
Abstract
The unregulated use of antimicrobial drugs and the evolution of bacterial selective pressure have led to an increasing number of drug-resistant pathogenic bacteria,which is a serious threat to livestock and poultry breeding as well as public health safety.With the development of nanotechnology,nano-drug delivery systems have shown a series of advantages in delivering antimicrobial drugs,such as improving the bioavailability of drugs,reducing the toxic side effects,and lowering the cost of drug use,which provide the new technologies and strategies for overcoming bacterial drug resistance.In this paper,we reviewed the progress of six nano-drug delivery system types of nanoemulsion,liposome,solid lipid nanoparticle,nano micelle,metal nanoparticle and nano gel in the prevention and control of drug-resistant pathogens,starting from the hazards of drug-resistant pathogens and the current status of their prevention and control in livestock and poultry.We expect to provide a reference for nano-drug delivery system application in the prevention and control of drug-resistant pathogen in livestock and poultry,and help the green and sustainable development of animal husbandry industry.关键词
抗菌药物/纳米药物递送系统/细菌感染/耐药性/畜禽养殖/可持续发展Key words
Antimicrobial drug/Nano-drug delivery system/Bacterial infection/Drug resistance/Animal breeding/Sustainable development分类
畜牧业引用本文复制引用
周宇峰,高馨,戴文青,崔娜,张鸿焱,廖晓萍..纳米药物递送系统在耐药病原菌防控中的研究进展[J].华南农业大学学报,2025,46(3):287-300,14.基金项目
国家重点研发计划(2023YFD1800100) （2023YFD1800100）
