基因与疾病(英文)2025,Vol.12Issue(3):76-79,4.DOI:10.1016/j.gendis.2024.101503
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy
Wei Zhang 1Peng Gong 1Yibao Fan 2Milad Ashrafizadeh 1Dan Shi 1Gautam Sethi 3Yavuz Nuri Ertas 4A.M.Abd El-Aty 5Xianbin Zhang 1Si Chen6
作者信息
- 1. Department of General Surgery,Institute of Precision Diagnosis and Treatment of Digestive System Tumors and Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics,Carson International Cancer Center,Shenzhen University General Hospital,Shenzhen University,Shenzhen,Guangdong 518055,China
- 2. Department of General Surgery,Institute of Precision Diagnosis and Treatment of Digestive System Tumors and Guangdong Provincial Key Laboratory of Chinese Medicine Ingredients and Gut Microbiomics,Carson International Cancer Center,Shenzhen University General Hospital,Shenzhen University,Shenzhen,Guangdong 518055,China||School of Pharmacy,Shenzhen University Medical School,Shenzhen,Guangdong 518060,China
- 3. Department of Pharmacology and NUS Centre for Cancer Research,Yong Loo Lin School of Medicine,National University of Singapore,Singapore 117600,Singapore
- 4. Department of Biomedical Engineering,Erciyes University,Kayseri 38039,Turkey||Department of Technical Sciences,Western Caspian University,AZ1001,Baku,Azerbaijan
- 5. Department of Pharmacology,Faculty of Veterinary Medicine,Cairo University,Giza 12211,Egypt||Department of Medical Pharmacology,Medical Faculty,Ataturk University,Erzurum 25240,Turkey
- 6. Department of Immunology,Shenzhen University Medical School,Shenzhen,Guangdong 518060,China
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Wei Zhang,Peng Gong,Yibao Fan,Milad Ashrafizadeh,Dan Shi,Gautam Sethi,Yavuz Nuri Ertas,A.M.Abd El-Aty,Xianbin Zhang,Si Chen..A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy[J].基因与疾病(英文),2025,12(3):76-79,4.基金项目
This study was supported by the National Natural Science Foundation of China(No.82405167),the Shenzhen Science and Technology Program(Guangdong,China)(No.GJHZ20220913143005010),and the fundamental research project of the Shenzhen Science and Technology Innovation Commission(No.20231120113324002 and No.RCBS20231211090635056). (No.82405167)