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Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells

Yang Wang Weiwei Yu Weiqiang Lu Bo Feng Jiacheng He Naijipu Abuduaini Wenjuan Liu Yuanjun Song Zunping Ke Xilong Wang Wei Jiao Si Chen Xianhua Lin

基因与疾病（英文）2025，Vol.12Issue(3)：80-83,4.

基因与疾病（英文）2025，Vol.12Issue(3)：80-83,4.DOI:10.1016/j.gendis.2024.101356

Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells

Yang Wang ¹Weiwei Yu ²Weiqiang Lu ²Bo Feng ³Jiacheng He ⁴Naijipu Abuduaini ³Wenjuan Liu ²Yuanjun Song ⁵Zunping Ke ⁶Xilong Wang ¹Wei Jiao ¹Si Chen ²Xianhua Lin²

作者信息

1. Department of Urology,The Fifth People's Hospital of Shanghai,Fudan University,Shanghai 200240,China
2. Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai 200241,China
3. Department of General Surgery,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200020,China
4. Joint Center for Translational Medicine,Shanghai Fifth People's Hospital,Fudan University and School of Life Science,East China Normal University,Shanghai 200240,China
5. Shanghai Municipal Health Commission,Shanghai 200125,China
6. Department of Gerontology,The Fifth People's Hospital of Shanghai,Fudan University,Shanghai 200240,China
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摘要

引用本文复制引用

Yang Wang,Weiwei Yu,Weiqiang Lu,Bo Feng,Jiacheng He,Naijipu Abuduaini,Wenjuan Liu,Yuanjun Song,Zunping Ke,Xilong Wang,Wei Jiao,Si Chen,Xianhua Lin..Shikonin is a novel antagonist of prostaglandin E2 receptor 4 that targets myeloid-derived suppressor cells[J].基因与疾病（英文）,2025,12(3):80-83,4.

基金项目

This work was supported by the Shanghai Key Medical Specialty Program(China)(No.ZK2019A03 to Y.W.),Natural Science Research Funds of Minhang District,Shanghai,China(No.2021MHZ071 to Y.W.),Scientific Research Proj-ect funded by Shanghai Fifth People's Hospital,Fudan University(No.2020WYZT02 to Y.W.),the National Natural Science Foundation of China(No.82373237 to B.F.,82172644 to W.Q.L),ECNU Multifunctional Platform for Innovation(011),and The Instruments Sharing Platform of School of Life Science,East China Normal University. （China）

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