菌物研究2025，Vol.23Issue(2)：93-106,14.DOI:10.13341/j.jfr.2024.1827
灵芝甾醇的化学成分及生物活性研究进展
Research Progress on Chemical Components and Biological Activity of Ganoderma Sterols
摘要
Abstract
Ganoderma sterols are important bioactive compounds,which are generally composed of ergosterol as the basic skeleton.Catalyzed by the hydroxylase and other post-modification enzymes,these kinds of compounds can generate various steroid derivatives carrying different molecular structures.Sterol compounds of Ganoderma are known to have pharmacological activity on anti-tumor,immune modulation,anti-inflammatory,and anti-aging.In this review,structures and pharmacological activities of 62 steroid compounds analyzed from Ganoderma sp.over the past 40 years are summarized together with future prospects for research and development directions of Ganoderma sterols to provide a theoretical flamework for the systematic study of Ganoderma sp.关键词
灵芝属/甾醇/化学成分/药理活性/系统化研究Key words
Ganoderma/sterol/chemical composition/bioactivity/systematic research分类
生物学引用本文复制引用
傅薇澄,吴卓清,陈天娇,陈晶晶,杨金玲,巩婷,朱平..灵芝甾醇的化学成分及生物活性研究进展[J].菌物研究,2025,23(2):93-106,14.基金项目
中国医学科学院重大协同创新工程项目(2023-I2M-2-006) （2023-I2M-2-006）
