菌物研究2025,Vol.23Issue(2):119-140,22.DOI:10.13341/j.jfr.2024.1747
轮层炭壳菌属真菌次级代谢产物及生物活性研究进展
Research Advances in Secondary Metabolites and Bioactivities of Daldinia Fungi
摘要
Abstract
The genus Daldinia,commonly known as"cramp balls"or"carbon balls",is of great importance as a type of wood-decaying fungus.Possessing distinctive capabilities,it is able to generate a diverse array of structurally novel secondary metabolites.These metabolites exhibit remarkable biological activities,which thus makes the Daldinia fungi as a pivotal resource for the exploration and development of bioactive pharmaceuticals.After a systematic summarization of related information from pertinent literature,this paper gives the first comprehensive overview of secondary metabolites produced by Daldinia fungi on the basis of scientific reports published from 1995 to 2023,together with their associated biological activities.Within this review,we generalize the contents for a number of 330 compounds that are divided into various categories including alkaloids,polyketides,terpenoids,volatile components and others.Moreover,we also provide available information on the wide-ranging biological activities of these compounds,including cytotoxicity,anti-inflammatory,antiviral,antioxidant,and antimicrobial properties with a purpose to bring a valuable reference for the further development and application of bioactive constituents present within this fungal genus.关键词
轮层炭壳菌属/次级代谢产物/生物活性Key words
Daldinia/secondary metabolites/biological activity分类
药学引用本文复制引用
俞静,李宜航,尹翠云,邓招游,唐德英,石选超,张丽霞..轮层炭壳菌属真菌次级代谢产物及生物活性研究进展[J].菌物研究,2025,23(2):119-140,22.基金项目
云南省重大科技专项计划项目(202102AA100020),云南省科技人才和平台计划项目(202205AF150071) (202102AA100020)