临床肝胆病杂志2025，Vol.41Issue(4)：773-777,5.DOI:10.12449/JCH250426
肠道菌群在失代偿期肝硬化并发急性肾损伤中的致病机制及相关靶向治疗
The role of gut microbiota in acute kidney injury in patients with decompensated liver cirrhosis and related targeted therapies
摘要
Abstract
Acute kidney injury(AKI)is a severe complication in patients with decompensated liver cirrhosis and tends to have a high mortality rate and a poor prognosis.Current studies have shown that gut microbiota might be associated with the development and progression of AKI,and it is necessary to pay attention to the application of targeted therapy based on gut microbiota in the prevention and treatment of such patients.Therefore,this article reviews the possible pathogenesis of gut microbiota in liver cirrhosis comorbid with AKI,as well as potential prevention and treatment measures targeting gut microbiota,in order to provide a reference for the pathogenesis of such patients and related treatment methods.关键词
肝硬化/急性肾损伤/胃肠道微生物组/治疗学Key words
Liver Cirrhosis/Acute Kidney Injury/Gastrointestinal Microbiome/Therapeutics引用本文复制引用
林清标,王贵强..肠道菌群在失代偿期肝硬化并发急性肾损伤中的致病机制及相关靶向治疗[J].临床肝胆病杂志,2025,41(4):773-777,5.基金项目
福建省自然科学基金(2023J011461) Natural Science Foundation of Fujian Province(2023J011461) （2023J011461）
