临床肝胆病杂志2025,Vol.41Issue(4):778-783,6.DOI:10.12449/JCH250427
肿瘤坏死因子超家族因子14(LIGHT)在慢性肝病中的作用机制
Mechanism of action of tumor necrosis factor superfamily member 14 in chronic liver diseases
摘要
Abstract
Tumor necrosis factor superfamily member 14(TNFSF14)is a new member of the tumor necrosis factor superfamily member,and it mediates diverse biological functions through binding with herpes virus entry mediator,lymphotoxin-β receptor,and soluble decoy receptor 3,thereby exerting an important regulatory effect in inflammatory diseases,fibrotic diseases,and anti-tumor immunity.In recent years,the mechanism of LIGHT in the development and progression of liver diseases and its role in treatment have attracted more and more attention.关键词
肿瘤坏死因子类/肝疾病/信号传导Key words
Tumor Necrosis Factors/Liver Diseases/Signal Transduction引用本文复制引用
马亚鹏,马亚楠..肿瘤坏死因子超家族因子14(LIGHT)在慢性肝病中的作用机制[J].临床肝胆病杂志,2025,41(4):778-783,6.基金项目
山西省自然科学基金(202303021222308) (202303021222308)
山西白求恩医院人才引进科研启动金(2023RC56) Shanxi Natural Science Foundation(202303021222308) (2023RC56)
Shanxi Bethune Hospital Talent Introduction Research Start-Up Fund(2023RC56) (2023RC56)