临床神经外科杂志2025，Vol.22Issue(2)：131-137,7.DOI:10.3969/j.issn.1672-7770.2025.02.003
血管内治疗和显微外科治疗颅内囊状未破裂动脉瘤的临床疗效评价:一项大型Meta分析
Clinical assessment of endovascular and microsurgical treatment for unruptured intracranial aneurysms:a large-scale meta-analysis
摘要
Abstract
Objective To evaluate the risk factors for clinical complications associated with endovascular treatment(EVT)and microsurgical treatment(MST).Methods PubMed,Cochrane Library,Web of Science,Karger and Thieme medical databases for studies published between January 1,2011 and August 30,2024 were retrieved.For studies reporting data on risk factors for complications,values of odds ratio(OR)with 95％confidence interval(CI)and pooled values were estimated by weighted random-effects model.Results Collective risk factors associated with both MST and EVT complications were diabetes mellitus[ORMST=1.45(95％CI=1.03-2.03),P＜0.001,OREVT=1.81(95％CI=1.05-3.13),P＜0.001],heart comorbidity[ORMST=2.81(95％CI=1.57-4.79),P＜0.001,OREVT=2.27(95％CI=1.53-3.37),P＜0.001],and posterior circulation aneurysm location[ORMST=7.22(95％CI=3.70-14.20),P＜0.001,OREVT=1.42(95％CI=1.15-1.74),P＜0.001].Conclusions This study identifies risk factors for surgical complications of unruptured intracranial aneurysms.However,multicentric prospective cohort studies are needed to further validate our findings in the future.关键词
颅内未破裂动脉瘤/血管内治疗/显微外科治疗/Meta分析Key words
unruptured intracranial aneurysm/endovascular treatment/microsurgical treatment/meta-analysis分类
临床医学引用本文复制引用
桑小丽,李晨曦,陈小红,郑亚杰,苏丽萍..血管内治疗和显微外科治疗颅内囊状未破裂动脉瘤的临床疗效评价:一项大型Meta分析[J].临床神经外科杂志,2025,22(2):131-137,7.基金项目
国家自然科学基金资助项目(82360256) （82360256）
省部共建中亚高发病成因与防治国家重点实验室开放课题项目(SKL-HIDCA-2022-JZ7) （SKL-HIDCA-2022-JZ7）
