临床神经外科杂志2025，Vol.22Issue(2)：143-148,6.DOI:10.3969/j.issn.1672-7770.2025.02.005
NLR对动脉瘤性蛛网膜下腔出血后脑积水的预测价值
Predictive value of neutrophil-to-lymphocyte ratio for hydrocephalus following aneurysmal subarachnoid hemorrhage
摘要
Abstract
Objective To investigate the predictive value of neutrophil-to-lymphocyte ratio(NLR)for hydrocephalus following aneurysmal subarachnoid hemorrhage(aSAH).Methods The clinical data of 88 aSAH patients admitted from January 2022 and November 2024 were analyzed retrospectively.Patients were categorized into hydrocephalus group(n=27)and non-hydrocephalus(n=61)group based on cranial CT findings.Demographic characteristics,comorbidities,and NLR were analyzed by univariate and multivariate logistic regression.Receiver operating characteristic(ROC)curves were generated to evaluate predictive performance.Results The hydrocephalus group had a significantly higher mean age(67.56±7.29 vs 57.41±10.84 years,P＜0.001),NLR(15.31±8.84 vs 7.90±5.79,P＜0.001)and diabetes prevalence(22.2％vs 4.9％,P=0.022).Multivariate analysis identified age(OR=1.12,95％CI=1.04-1.20,P=0.002),diabetes(OR=6.34,95％CI=1.01-39.78,P=0.049),and NLR(OR=1.21,95％CI=1.09-1.34,P＜0.001)as independent risk factors.ROC analysis revealed that NLR(AUC=0.791)outperformed age(AUC=0.778)and diabetes(AUC=0.587).The combined model achieved an AUC of 0.874.Conclusions NLR is an independent predictor of hydrocephalus after aSAH.Integrating NLR with age and diabetes history enhances predictive accuracy,aiding early clinical intervention.关键词
中性粒细胞与淋巴细胞比值/动脉瘤性蛛网膜下腔出血/脑积水/炎症标志物/预后预测Key words
neutrophil-to-lymphocyte ratio/aneurysmal subarachnoid hemorrhage/hydrocephalus/inflammatory biomarker/prognostic prediction分类
临床医学引用本文复制引用
任祎,佟建洲,孙文栋,张向前,张磊..NLR对动脉瘤性蛛网膜下腔出血后脑积水的预测价值[J].临床神经外科杂志,2025,22(2):143-148,6.基金项目
保定市科技计划项目(2241ZF055) （2241ZF055）
