摘要
Abstract
Objective To summarize the clinical features of patients with acute immune sensory polyneuropathy(AISP),in order to further understand the disease.Methods A retrospective analysis was conducted on the clinical presentation,physical examination,laboratory tests,electrophysiological examination,imaging studies,and treatment process of one AISP patient.Results A 54-year-old male patient presented with acute onset,with no obvious history of preceding infection.The condition progressed rapidly,primarily manifested as sensory disturbances,with both superficial and deep sensations affected.Laboratory tests revealed protein-cell dissociation in cerebrospinal fluid and positive anti-amphiphysin antibodies in the serum.Electromyography showed normal sensory nerve conduction,while Somatosensory Evoked Potentials(SEPs)were abnormal.The patient's symptoms significantly improved after receiving intravenous im-munoglobulin and low-dose corticosteroid treatment.One-year follow-up showed complete resolution of symptoms with no recurrence.Conclusions Patients with AISP typically have an acute onset.Clinical features include sensory ataxia,normal motor function,reduced or absent tendon reflexes,cerebrospinal fluid protein-cell dissociation,normal nerve con-duction on electromyography,and abnormal SEP.Immunotherapy is effective,and the disease course is monophasic.AISP is rarely seen in clinical practice,and early recognition and immunotherapy can significantly improve prognosis.关键词
急性免疫性感觉性多发性神经根病/吉兰-巴雷综合征/感觉性共济失调/抗amphiphysin抗体/免疫治疗Key words
acute immune sensory polyneuropathy/Guillain-Barré syndrome/sensory ataxia/anti-amphiphysin antibodies/immunotherapy分类
医药卫生
