山东医药2025，Vol.65Issue(4)：128-131,135,5.DOI:10.3969/j.issn.1002-266X.2025.04.026
腹膜透析相关腹膜纤维化的防治策略研究进展
Research progress on prevention and treatment strategies for peritoneal fibrosis related to peritoneal dialysis
摘要
Abstract
Peritoneal dialysis is an effective renal replacement therapy for patients with end-stage renal disease.How-ever,long-term exposure of the peritoneum to high-glucose dialysis solutions can easily induce peritoneal fibrosis,which subsequently alters the structure and function of the peritoneum,ultimately leading to the failure of peritoneal dialysis ther-apy.Currently,clinical methods for preventing and treating peritoneal fibrosis are limited,primarily including pharmaco-logical interventions,and interventions of improving the biocompatibility of dialysis solutions,and others.Nevertheless,these approaches necessitate ongoing refinement and novel advancements.In-depth research into prevention and treatment strategies for peritoneal fibrosis holds significant importance for early prevention of its occurrence,extending the duration of peritoneal dialysis therapy,and enhancing the clinical efficacy of peritoneal dialysis.关键词
腹膜透析/腹膜纤维化/钠-葡萄糖协同转运蛋白2抑制剂/生物相容性Key words
peritoneal dialysis/peritoneal fibrosis/sodium-glucose cotransporter 2(SGLT2)inhibitor/biocompat-ibility分类
医药卫生引用本文复制引用
刘萌萌,张秋花..腹膜透析相关腹膜纤维化的防治策略研究进展[J].山东医药,2025,65(4):128-131,135,5.基金项目
江苏省无锡市卫健委中青年拔尖人才资助计划项目(HB2023029). （HB2023029）
