山东医药2025，Vol.65Issue(4)：141-145,5.DOI:10.3969/j.issn.1002-266X.2025.04.029
干细胞疗法和3D打印技术在烧伤患者创面汗腺再生治疗中的应用进展
Advances in application of stem cell therapy and 3D printing technology for sweat gland regeneration in wounds of burn patients
摘要
Abstract
Burns represent a significant cause of damage to the skin and its appendages.Deep second-degree burns and more severe injuries can destroy the structure of sweat glands,leading to impaired perspiration function.Sweat gland regeneration is essential for functional recovery in burn patients.Stem cell therapy promotes sweat gland regeneration by le-veraging mesenchymal stem cells,epidermal stem cells,and induced pluripotent stem cells to modulate the wound micro-environment and induce differentiation into sweat gland-like cells.Meanwhile,3D printing technology precisely constructs complex biological scaffolds that mimic the dermal matrix during sweat gland development,providing an optimal environ-ment for stem cell differentiation and sweat gland regeneration,thereby facilitating the restoration of sweat gland function.Both approaches offer promising new treatment strategies for burn patients,but further development is still required.关键词
干细胞疗法/3D打印技术/烧伤/创面汗腺再生Key words
stem cell therapy/3D printing/burn/regeneration of sweat glands分类
医药卫生引用本文复制引用
扈煜婕,陆美琪,姜笃银..干细胞疗法和3D打印技术在烧伤患者创面汗腺再生治疗中的应用进展[J].山东医药,2025,65(4):141-145,5.基金项目
国家自然科学基金资助项目(81873934) （81873934）
山东省济南市科技计划(后补助)项目(202225065). （后补助）
