实用中医内科杂志2025，Vol.39Issue(4)：16-19,4.DOI:10.13729/j.issn.1671-7813.Z24110605
基于络病理论探讨巨噬细胞M1/M2 极化与特发性肺纤维化"肺热络瘀"间的联系
The Relation of M1/M2 Macrophage Polarization in ＂Lung Heat and Collaterals Stasis＂of Idiopathic Pulmonary Fibrosis(IPF)Based on the Collateral Disease Theory
摘要
Abstract
Idiopathic pulmonary fibrosis(IPF)is a chronic fibrotic interstitial pneumonia with unknown cause.Macrophages have emerged as an important contributor to the pathogenesis of fibrosis over the past decade.This article summarizes the role of M1 and M2 macrophages in IPF and expounds the dynamic evolution of M1/M2 polarization in IPF.Based on the theory of loxop-athy,the author analyses the correlation between IPF'lung heat and collaterals stasis'and the dynamic evolution of M1/M2 macrophage polarization in IPF,so as to provide new ideas for its prevention and treatment.关键词
特发性肺纤维化/络病理论/肺热络瘀/巨噬细胞/M1/M2 极化Key words
Idiopathic pulmonary fibrosis(IPF)/Collateral Disease Theory/lung heat and collaterals stasis/Macrophages/M1/M2 polarization分类
医药卫生引用本文复制引用
彭成飞,庞立健,吕晓东,王琳琳,孙婉宁,刘鑫瑶,崔杨..基于络病理论探讨巨噬细胞M1/M2 极化与特发性肺纤维化"肺热络瘀"间的联系[J].实用中医内科杂志,2025,39(4):16-19,4.基金项目
国家自然科学基金面上项目(82274440) （82274440）
