护理研究2025，Vol.39Issue(8)：1293-1303,11.DOI:10.12102/j.issn.1009-6493.2025.08.009
非药物干预措施改善血液透析病人不宁腿综合征的网状Meta分析
Non-pharmacological interventions for improving restless legs syndrome in hemodialysis patients:a network Meta-analysis
摘要
Abstract
Objective:To evaluate the effect of different non-pharmacological interventions on restless legs syndrome in hemodialysis patients by network meta-analysis,and to provide evidence for clinical nursing.Methods:The relevant randomized controlled trials in PubMed,CINAHL,the Cochrane Library,EMbase,Web of Science,CNKI,WanFang database,VIP,and CBM databases were searched by computer.The retrieval time was from database establishment to November 30,2023.The quality of the included literatures was evaluated using the Cochrane handbook.A network Meta-analysis was performed using StataSE 15.0 software to rank interventions by cumulative ranking of areas under the probability curve.Funnel plot was drawn for publication bias test.Results:A total of 33 articles were included,involving 2 065 patients,including 22 non-pharmacological interventions.Network Meta-analysis results showed,cool dialysate,lavender essential oil massage,glycerin massage,sweet orange essential oil massage,acupoint application,Chinese medicine foot bath combined with acupuncture,reflexology,Chinese medicine foot bath and point massage,bicycle exercise and Chinese medicine foot bath were superior to the control group in improving the symptoms of restless legs in dialysis patients,SUCRA values were 99.6％,92.2％,75.4％,72.1％,67.9％,67.4％,65.6％,57.2％,47.7％,and 41.9％,respectively.Stretching exercises were the most effective in improving sleep,followed by reflexology and aerobic exercise,SUCRA values were 84.0％,80.7％and 79.4％,respectively.Conclusion:Non-pharmacological intervention has obvious effect on the improvement of restless legs syndrome in hemodialysis patients.Low temperature dialysis is the best intervention measure to improve restless leg symptoms in hemodialysis patients.And stretching exercise is the best intervention measure to improve sleep conditions.In the future,evidence-based non-pharmacological interventions could be used in clinical practice.关键词
非药物干预/血液透析/不宁腿综合征/网状Meta分析/循证护理Key words
non-pharmacological intervention/hemodialysis/restless legs syndrome/network Meta-analysis/evidence-based nursing引用本文复制引用
常钟文,赵倩,何亚鹏,徐惠泽,赵剑,朱东阁,韩明华..非药物干预措施改善血液透析病人不宁腿综合征的网状Meta分析[J].护理研究,2025,39(8):1293-1303,11.基金项目
中国研究型医学院学会护理分会2022年临床护理研究课题,编号:Y2022FH-HLFH06-09 （）
中华医学会杂志社2022-2023年护理学科研究课题,编号:CMAPH-NRD2022034 （）
