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抗氧化高分子在生物医学应用中的研究进展

周同 张楠 石立旺 方昭 张晨曦 祝纶宇

石油化工2025,Vol.54Issue(4):567-575,9.
石油化工2025,Vol.54Issue(4):567-575,9.DOI:10.3969/j.issn.1000-8144.2025.04.017

抗氧化高分子在生物医学应用中的研究进展

Research progress in antioxidant macromolecules applied in biomedicine

周同 1张楠 1石立旺 1方昭 1张晨曦 1祝纶宇1

作者信息

  • 1. 中石化(北京)化工研究院有限公司中国石化医用卫生材料研究与应用重点实验室,北京 100013
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摘要

Abstract

Antioxidants have been widely regarded as a kind of potential therapeutics thanks to their capabilities of delaying and/or inhibiting oxidative stress in the pathological micro-environment.Compared with similar small molecules,antioxidant macromolecules have better stability and longer retention time,resulting in stronger reactive oxygen species(ROS)scavenging ability in vivo.Common antioxidant macromolecules with different antioxidant groups were reviewed.The structure of functional groups,mechanism of ROS scavenging,preparation methods,and application of these polymers in biomedical fields were introduced.Their advantages and challenges were further discussed.

关键词

抗氧化高分子/活性氧/炎症/疾病治疗

Key words

antioxidant macromolecules/reactive oxygen species/inflammation/disease treatment

分类

化学化工

引用本文复制引用

周同,张楠,石立旺,方昭,张晨曦,祝纶宇..抗氧化高分子在生物医学应用中的研究进展[J].石油化工,2025,54(4):567-575,9.

基金项目

中国石油化工集团公司资助项目(223090). (223090)

石油化工

OA北大核心

1000-8144

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