世界中医药2025,Vol.20Issue(2):283-288,6.DOI:10.3969/j.issn.1673-7202.2025.02.014
侧隐窝注射联合超声下深刺八髎穴治疗腰椎间盘突出症临床研究
Treatment of Lumbar Disc Herniation by Lateral Recess Injection Combined with Deep Needling of"Baliao"Acupoints under Ultrasound Localization
摘要
Abstract
Objective:To observe the clinical efficacy of lateral recess injection combined with deep needling of"Baliao"acu-points under ultrasound localization in the treatment of lumbar disc herniation.Methods:A total of 100 patients with lumbar disc herniation were randomly divided into a control group(n=50)and an observation group(n=50).The control group received later-al recess injection therapy alone,while the observation group received additional deep needling of"Baliao"acupoints under ultra-sound localization.Clinical efficacy was evaluated using the visual analog scale(VAS),Japanese Orthopedic Association(JOA)score,plasma thromboxane B2(TXB2)levels,plasma prostaglandin E2(PGE2)levels,serum tumor necrosis factor-α(TNF-α)lev-els,nuclear factor kappa B(NF-κB)protein phosphorylation levels,and the Macnab criteria before and after treatment.Results:Af-ter treatment,both groups showed a significant reduction in VAS scores compared to baseline,with the observation group showing superior improvement(P<0.05).JOA scores increased in both groups,with the observation group demonstrating better outcomes(P<0.05).Levels of inflammatory mediators(plasma TXB2,PGE2,and TNF-α)decreased in both groups,with greater reductions in the observation group(P<0.05).NF-κB protein phosphorylation levels also decreased in both groups,with the observation group exhibiting a more pronounced decrease(P<0.05).The overall efficacy rate in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:Lateral recess injection combined with deep needling of"Baliao"acupoints un-der ultrasound localization is an effective and reproducible treatment for lumbar disc herniation,with confirmed efficacy and simple clinical application.关键词
侧隐窝注射/腰椎间盘突出症/超声引导/针刺/八髎穴/炎症介质/NF-κB蛋白磷酸化水平/中西医结合Key words
Lateral recess injection/Lumbar disc herniation/Ultrasonic guidance/Acupuncture/"Baliao"acupoints/Inflammatory factor/NF-κB protein phosphorylation level/Combination of traditional Chinese and Western medicine分类
中医学引用本文复制引用
蒋晨浩,张建楠,周红梅,李荣华,杨慧慧,曹伟,刘砂金,蔡靓羽..侧隐窝注射联合超声下深刺八髎穴治疗腰椎间盘突出症临床研究[J].世界中医药,2025,20(2):283-288,6.基金项目
国家自然科学基金项目(81973878) (81973878)
江苏省自然科学基金项目(BK20180167) (BK20180167)
江苏中医药领军人才项目(SLJ0218) (SLJ0218)
无锡市中医药管理局一般项目(ZYKJ202107) (ZYKJ202107)