摘要
Abstract
Objective To explore the anesthetic effect of Sufentanil in laparoscopic surgery for hysteromyoma and its influence on immune function.Methods A total of 80 patients who were treated by laparoscopic surgery for hysteromyoma from August 2022 to February 2024 in Dingzhou People's Hospital were selected as the study objects and divided into two groups using the random number table method,with 40 cases in each group.Both groups received general anesthesia by tracheal intubation.Sufentanil was used in the observation group and Fentanyl was used in the control group.The humoral immunity indexes,cellular immunity indexes,anesthesia resuscitation indexes,and incidence of adverse reactions were compared between the two groups.Results After anaesthesia,the levels of humoral immunity indexes(immunoglobulin A,immunoglobulin G,and immunoglobulin M)in the observation group were higher than those in the control group(P<0.05).After anaesthesia,the CD4+,CD8+,and CD4+/CD8+in the observation group were higher than those in the control group(P<0.05).The awakening time,extubation time,and recovery room stay time in the observation group were shorter than those in the control group(P<0.05).The total incidence of adverse reactions(nausea and vomiting,skin itching,hypotension,and arrhythmia)in the observation group was lower than that in the control group(P<0.05).Conclusion Compared with Fentanyl,Sufentanil used in laparoscopic surgery for hysteromyoma has less influence on immune function,and faster postoperative recovery.关键词
舒芬太尼/子宫肌瘤/腹腔镜手术/细胞免疫/体液免疫Key words
Sufentanil/Hysteromyoma/Laparoscopic surgery/Cellular immunity/Humoral immunity分类
医药卫生
