上海针灸杂志2025，Vol.44Issue(4)：429-433,5.DOI:10.13460/j.issn.1005-0957.2025.04.0429
针刺治疗乳腺癌内分泌治疗后心肾不交型汗证的疗效观察
Observation on the efficacy of acupuncture for hyperhidrosis of heart-kidney disharmony type after endocrine therapy for breast cancer
摘要
Abstract
Objective To observe the clinical efficacy of acupuncture at combined points Yinxi(HT6)and Fuliu(KI7)for hyperhidrosis of heart-kidney disharmony type after endocrine therapy for premenopausal breast cancer.Method Eighty patients with hyperhidrosis of heart-kidney disharmony type after endocrine therapy for premenopausal breast cancer were allocated,using a randomized controlled method,to an observation group(40 cases)and a control group(40 cases).During the study,two cases dropped out in the observation group and one case,in the control group because they did not completely comply with the study requirements.Finally,77 cases were included for statistical analysis,38 in the observation group and 39 in the control group.The observation group received acupuncture at combined points Yinxi and Fuliu and the control group,sham acupuncture with shallow needling at non-acupoints.The TCM symptom score,the hyperhidrosis disease severity scale(HDSS)score,the self-rating anxiety scale(SAS)score and the self-rating depression scale(SDS)score were recorded and serum hormone[estradiol(E2),follicle stimulating hormone(FSH)and luteinizing hormone(LH)]levels were measured in the two groups before and after treatment.The clinical therapeutic effects were compared between the two groups.Result The total efficacy rate was 94.7%in the observation group,which was significantly higher than 56.4%in the control group(P＜0.05).After treatment,the HDSS score was better in the observation group compared with before(P＜0.05)and than in the control group(P＜0.05).After treatment,the SAS and SDS scores decreased in the two groups compared with before(P＜0.05)and were lower in the observation group than in the control group(P＜0.05).There were no statistically significant pre-treatment and post-treatment differences in serum E2,FSH and LH levels between the two groups and no statistically significant within-group differences after treatment(P＜0.05).Conclusion Acupuncture at combined points Yinxi and Fuliu can effectively alleviate hyperhidrosis of heart-kidney disharmony type after endocrine therapy for premenopausal breast cancer and relieve depressive and anxiety states.关键词
针刺疗法/假针刺/汗证/心肾不交/乳腺癌/内分泌治疗Key words
Acupuncture therapy/Sham acupuncture/Hyperhidrosis/Heart-kidney disharmony/Breast cancer/Endocrine therapy分类
医药卫生引用本文复制引用
覃霄燕,李鸿章,王洪宇,刘奕兵,白瑞莉..针刺治疗乳腺癌内分泌治疗后心肾不交型汗证的疗效观察[J].上海针灸杂志,2025,44(4):429-433,5.基金项目
河南省科技攻关计划项目(LHGJ20200724) （LHGJ20200724）
郑州市中医药骨干人才培养项目[郑卫管(2023)25号] （2023）
