上海针灸杂志2025，Vol.44Issue(4)：434-439,6.DOI:10.13460/j.issn.1005-0957.2024.13.4023
电针对肺癌术后肺炎及心肺功能的影响
Effect of electroacupuncture on pneumonia and cardiopulmonary function after lung cancer surgery
摘要
Abstract
Objective To observe the effects of electroacupuncture on pneumonia and cardiopulmonary function in patients in the early stage after receiving surgery for lung cancer.Method Sixty-eight patients with lung cancer who received thoracoscopic radical resection of lung cancer under general anesthesia were selected and randomized into a control group and an observation group,with 34 cases in each group.The control group received the combined intravenous and inhalation anesthesia,and the observation group additionally received electroacupuncture beginning 30 min before the induction of anesthesia till the end of the operation.Before the operation(T0),at the end of the operation(T1),at postoperative 24 h(T2),and at postoperative 72 h(T3),the two groups were observed for changes in blood gas analysis parameters[PaO2,PaCO2,and PaO2/FiO2],serum inflammatory indicators[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and procalcitonin(PCT)],white blood cell count(WBC),and cardiopulmonary function indexes[peak expiratory flow(PEF)and 6-minute walk distance(6MWD)].The two groups were also compared in the incidence of postoperative pneumonia,pain,and other complications.Result Compared to T0,both groups showed decreased PaO2 and PaO2/FiO2 at T1 and T2(P＜0.05)and increased PaCO2 at T1(P＜0.05);the two groups demonstrated increases in the serum levels of TNF-α,IL-6,and PCT as well as WBC at T1,T2,and T3(P＜0.05)and decreases in the PEF and 6MWD at T2 and T3(P＜0.05).At T2,the observation group was higher than the control group in comparing PaO2 and PaO2/FiO2(P＜0.05);at T1 and T2,the serum levels of TNF-α,IL-6,and PCT and WBC were lower in the observation group than in the control group(P＜0.05);at T2 and T3,the observation group had higher PEF and 6MWD than the control group(P＜0.05);at T2,the incidence rates of postoperative pneumonia and nausea and vomiting were lower in the observation group than in the control group(P＜0.05),and the observation group had a lower visual analog scale(VAS)score compared to the control group(P＜0.05).Conclusion Electroacupuncture can accelerate pulmonary recovery in the early stage after the operation by reducing postoperative inflammatory responses and pain and improving postoperative pulmonary dysfunction.关键词
针刺疗法/电针/疼痛,术后/肺癌/炎症因子/肺功能/术后肺炎Key words
Acupuncture therapy/Electroacupuncture/Pain,Postoperative/Lung cancer/Inflammatory factors/Pulmonary function/Postoperative pneumonia分类
医药卫生引用本文复制引用
王翔锋,黄建斌,林树英,李紫嫣,罗颖,林芩..电针对肺癌术后肺炎及心肺功能的影响[J].上海针灸杂志,2025,44(4):434-439,6.基金项目
国家中医临床研究基地专项科研课题(JDZX201926) （JDZX201926）
