妇儿健康导刊2025，Vol.4Issue(8)：65-68,106,5.DOI:10.3969/j.issn.2097-115X.2025.08.012
米诺环素联合甲泼尼龙、阿奇霉素序贯治疗难治性肺炎支原体肺炎患儿的临床效果
Clinical effect of Minocycline combined with Methylprednisolone and Azithromycin sequential therapy in the treatment of children with refractory Mycoplasma pneumoniae pneumonia
刘文伟 1逯遥 1郭金1
作者信息
- 1. 江苏省苏州明基医院,江苏 苏州 215009
- 折叠
摘要
Abstract
Objective To observe the clinical effect of Minocycline combined with Methylprednisolone and Azithromycin sequential therapy in the treatment of children with refractory Mycoplasma pneumoniae pneumonia(RMPP).Methods Ninety-eight children with RMPP in Suzhou BENQ Medical Center from April 2023 to April 2024 were selected and divided into two groups according to different medication methods,with 49 cases in each group.The conventional group was given Azithromycin sequential therapy combined with Methylprednisolone,and the study group was given Minocycline on the basis of conventional group.The therapeutic effect of the two groups was compared.Results After treatment,the levels of inflammatory factors in both groups were lower than those before treatment,and the levels of inflammatory factor in the study group were lower than those in the conventional group(P<0.05).The disappearance time of clinical symptoms in the study group was shorter than that in the conventional group(P<0.05).The respiratory function of the two groups was improved compared with that before treatment,and the respiratory function of the study group was better than that of the conventional group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Minocycline combined with Methylprednisolone and Azithromycin sequential therapy in the treatment of children with RMPP can reduce the levels of inflammatory factor,shorten the disappearance time of symptoms,and improve respiratory function.关键词
米诺环素/甲泼尼龙/难治性肺炎支原体肺炎/炎症因子Key words
Minocycline/Methylprednisolone/Refractory Mycoplasma pneumoniae pneumonia/Inflammatory factor分类
医药卫生引用本文复制引用
刘文伟,逯遥,郭金..米诺环素联合甲泼尼龙、阿奇霉素序贯治疗难治性肺炎支原体肺炎患儿的临床效果[J].妇儿健康导刊,2025,4(8):65-68,106,5.
