摘要
Abstract
Objective To analyze the efficacy of ultrasound-guided radiofrequency ablation(FRA)in the treatment of small primary hepatic cancer(PHC),and to analyze the risk factors of death.Methods 100 patients with small PHC from March 2020 to January 2024 were selected and treated with ultrasound-guided FRA.The therapeutic effect was evaluated 1 month after treatment,and a 2-year follow-up was conducted.Univariate and multivariate Logistic analysis were used to analyze the factors affecting the death of patients.Results The recent total effective rate of 100 patients was 73.00％;the 1-year follow-up survival rate was 90.00％,and the 2-year follow-up survival rate was 77.00％.No statistical difference showed in age,gender,ALB,hepatitis,ALT and AST between survival and death patients(P＞0.05).However,the serum AFP,the proportion of blood vessels adjacent to the lesion,the proportion of Child Pugh grade C,tumor cell differentiation,and the proportion of patients who did not receive antiviral treatment in dead patients were higher than those in survival patients(P＜0.05);multivariate Logistic regression analysis showed that the independent risk factors of death in patients with small PHC were blood vessels adjacent to the lesion,serum AFP,no antiviral treatment,and Child Pugh C(P＜0.05).Conclusions Ultrasound-guided RFA therapy for small PHC has good short-term efficacy.Mastering the factors that affect the long-term survival of patients and taking active treatment may prolong the survival time of patients.关键词
小原发性肝癌/超声引导/死亡危险因素/射频消融Key words
Small primary hepatic cancer/Ultrasound-guided/Risk factor of death/Radiofrequency ablation分类
医药卫生
