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Enhancement of apoptosis in HCT116 and HepG2 cells by Coix lacryma-jobi var.lacryma-jobi seed extract in combination with sorafenib

Supawadee Parhira Piyarat Srisawang Guoyuan Zhu Apirath Wangteeraprasert Suphunwadee Sawong Pennapha Suknoppakit Julintorn Somran Naphat Kaewpaeng Khemmachat Pansooksan Dumrongsak Pekthong

中草药（英文版）2025，Vol.17Issue(2)：322-339,18.

中草药（英文版）2025，Vol.17Issue(2)：322-339,18.DOI:10.1016/j.chmed.2025.02.005

Enhancement of apoptosis in HCT116 and HepG2 cells by Coix lacryma-jobi var.lacryma-jobi seed extract in combination with sorafenib

Supawadee Parhira ¹Piyarat Srisawang ²Guoyuan Zhu ³Apirath Wangteeraprasert ⁴Suphunwadee Sawong ⁵Pennapha Suknoppakit ⁵Julintorn Somran ⁶Naphat Kaewpaeng ⁷Khemmachat Pansooksan ⁷Dumrongsak Pekthong⁸

作者信息

1. Department of Pharmaceutical Technology,Faculty of Pharmaceutical Sciences,Naresuan University,Phitsanulok 65000,Thailand||Center of Excellence for Innovation in Chemistry,Naresuan University,Phitsanulok 65000,Thailand||Center of Excellence for Environmental Health and Toxicology,Faculty of Pharmaceutical Sciences,Naresuan University,Phitsanulok 65000,Thailand
2. Center of Excellence for Innovation in Chemistry,Naresuan University,Phitsanulok 65000,Thailand||Department of Physiology,Faculty of Medical Science,Naresuan University,Phitsanulok 65000,Thailand||Center of Excellence in Medical Biotechnology,Faculty of Medical Science,Naresuan University,Phitsanulok 65000,Thailand
3. State Key Laboratory of Quality Research in Chinese Medicine,Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology,Taipa 999078,Macau
4. Department of Medicine,Faculty of Medicine,Naresuan University,Phitsanulok 65000,Thailand
5. Department of Physiology,Faculty of Medical Science,Naresuan University,Phitsanulok 65000,Thailand
6. Department of Pathology,Faculty of Medicine,Naresuan University,Phitsanulok 65000,Thailand
7. Center of Excellence for Innovation in Chemistry,Naresuan University,Phitsanulok 65000,Thailand||Department of Pharmaceutical Chemistry and Pharmacognosy,Faculty of Pharmaceutical Sciences,Naresuan University,Phitsanulok 65000,Thailand
8. Center of Excellence for Innovation in Chemistry,Naresuan University,Phitsanulok 65000,Thailand||Center of Excellence for Environmental Health and Toxicology,Faculty of Pharmaceutical Sciences,Naresuan University,Phitsanulok 65000,Thailand||Department of Pharmacy Practice,Faculty of Pharmaceutical Sciences,Naresuan University,Phitsanulok 65000,Thailand
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摘要

关键词

apoptosis/Coix lacryma-jobi var.lacryma-jobi/HCT116/HepG2/PI3K/AKT/mTOR pathway/reactive oxygen species/seed extracts/sorafenib

Key words

apoptosis/Coix lacryma-jobi var.lacryma-jobi/HCT116/HepG2/PI3K/AKT/mTOR pathway/reactive oxygen species/seed extracts/sorafenib

引用本文复制引用

Supawadee Parhira,Piyarat Srisawang,Guoyuan Zhu,Apirath Wangteeraprasert,Suphunwadee Sawong,Pennapha Suknoppakit,Julintorn Somran,Naphat Kaewpaeng,Khemmachat Pansooksan,Dumrongsak Pekthong..Enhancement of apoptosis in HCT116 and HepG2 cells by Coix lacryma-jobi var.lacryma-jobi seed extract in combination with sorafenib[J].中草药（英文版）,2025,17(2):322-339,18.

基金项目

This work was supported by the National Science Research and Innovation Fund(NSRF)of Thailand(No.R2565B045),the Global and Frontier Research University Fund,(No.R2567C003),Naresuan University,Thailand.The funders played no part in study design,data collection and analysis,publication decisions,or manuscript writing. （NSRF）

中草药（英文版）

ISSN：1674-6384

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