烟草科技2025，Vol.58Issue(4)：20-25,6.DOI:10.16135/j.issn1002-0861.2024.0640
2,3-二氢-6-甲基-3,5-二羟基-4H-吡喃-4-酮碳酸酯的合成及热裂解
Synthesis and pyrolysis of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one carbonates
摘要
Abstract
To address the challenge of easy oxidative decomposition of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one(DDMP),two stable tobacco flavor materials,DDMP carbonate diester and DDMP carbonate triester,were synthesized using DDMP as the raw material.The structure of the target products was characterized using 1H NMR,13C NMR and HRMS techniques.Thermal gravimetric and pyrolysis analyses of DDMP carbonate diester and DDMP carbonate triester were performed using on-line pyrolysis gas chromatography/mass spectrometry(Py-GC-MS)technology.The results showed that:1)Between 200-300 ℃,both DDMP carbonate diester and DDMP carbonate triester rapidly lost weight as a result of broken carbonate bond.2)The main decomposition products of DDMP carbonate diester and DDMP carbonate triester were DDMP,furan and pyran compounds.3)After adding DDMP carbonate diester and DDMP carbonate triester compounds to unflavored cigarettes,the transfer rates of DDMP in the mainstream smoke of the above cigarettes were 4.95％and 4.69％,respectively.In addition,the transfer rates of DDMP remained essentially the same within 90 days.This method could improve the flavor release stability of DDMP in cigarettes.关键词
2,3-二氢-6-甲基-3,5-二羟基-4H-吡喃-4-酮/碳酸酯/前体化合物/热裂解/转移率Key words
2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one/Carbonate/Precursor compound/Pyrolysis/Transfer rate分类
轻工业引用本文复制引用
王清福,李蕾,赵嘉鸣,宁一博,王泽宁,席高磊,白冰,陈芝飞..2,3-二氢-6-甲基-3,5-二羟基-4H-吡喃-4-酮碳酸酯的合成及热裂解[J].烟草科技,2025,58(4):20-25,6.基金项目
河南中烟工业有限责任公司科技项目"吡喃酮类烟草甜味剂开发及应用技术研究"(ZW201810) （ZW201810）
河南省科技攻关项目"基于抗氧化策略的吡喃酮氧钒的合成及其抑制PTP1B活性研究"(242102310474). （242102310474）
