中风与神经疾病杂志2025，Vol.42Issue(4)：306-309,4.DOI:10.19845/j.cnki.zfysjjbzz.2025.0061
特发性震颤的非运动症状及黑质超声的相关研究
Features of non-motor symptoms and substantia nigra ultrasound in essential tremor
摘要
Abstract
Objective To investigate the features of non-motor symptoms and transcranial substantia nigra ultra-sound in essential tremor(ET).Methods General data were collected from 50 patients with ET and 50 healthy controls,and non-motor symptom scales and transcranial nigra sonography(TCS)were used for assessment.The t-test,the non-parametric test,and the chi-square test were used for comparison of general data,scale assessment results,and TCS find-ings between the two groups.Results There were significant differences between the ET group and the healthy control group in the total scores of NMSS,MoCA,HAMA,HAMD,PSQI,ESS,and FSS and the incidence rates of cognitive im-pairment,moderate or severe anxiety,poor sleep,and daytime sleepiness,while there were no significant differences in the incidence rates of moderate or severe depression and fatigue between the two groups.There were no significant differ-ences between the two groups in terms of"hyperechoic area of the left side""hyperechoic area of the right side""hyper-echoic area of both sides""S/M value""the number of cases with a hyperechoic area of>0.2 cm2 for at least one side""the number of cases with an S/M ratio of>7%"and"the number of cases with positive TCS results".Conclusion Com-pared with healthy controls,ET patients are more susceptible to cognitive impairment,anxiety,depression,poor sleep quality,daytime sleepiness,and fatigue,and the non-motor symptoms of ET should be taken seriously in clinical prac-tice.TCS examination has a relatively low diagnostic value in ET patients and healthy individuals.关键词
特发性震颤/非运动症状/经颅黑质超声Key words
Essential tremor/Non-motor symptom/Transcranial substantia nigra sonography分类
临床医学引用本文复制引用
陈学姣,邢秀颖,刘彬,任宁,李欣,陈蕾..特发性震颤的非运动症状及黑质超声的相关研究[J].中风与神经疾病杂志,2025,42(4):306-309,4.基金项目
天津市教委科研计划项目(自然科学)(2024ZD064) （自然科学）
