首页|期刊导航|药物分析学报（英文）|Phillygenin ameliorates tight junction proteins reduction,fibrosis,and apoptosis in mice with chronic colitis via TGR5-mediated PERK-eIF2α-Ca2+pathway

Phillygenin ameliorates tight junction proteins reduction,fibrosis,and apoptosis in mice with chronic colitis via TGR5-mediated PERK-eIF2α-Ca2+pathway

Huanhuan Xue Peijie Li Jing Guo Tinggui Chen Shifei Li Liwei Zhang

药物分析学报（英文）2025，Vol.15Issue(1)：172-188,17.

药物分析学报（英文）2025，Vol.15Issue(1)：172-188,17.DOI:10.1016/j.jpha.2024.101042

Phillygenin ameliorates tight junction proteins reduction,fibrosis,and apoptosis in mice with chronic colitis via TGR5-mediated PERK-eIF2α-Ca2+pathway

Huanhuan Xue ¹Peijie Li ¹Jing Guo ²Tinggui Chen ³Shifei Li ³Liwei Zhang³

作者信息

1. Institute of Molecular Science,Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Shanxi University,Taiyuan,030006,China||Modern Research Center for Traditional Chinese Medicine,Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Shanxi University,Taiyuan,030006,China
2. School of Ethnic-Minority Medicine,Guizhou Minzu University,Guiyang,550025,China
3. Institute of Molecular Science,Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Shanxi University,Taiyuan,030006,China
折叠

摘要

关键词

Ulcerative colitis/Phillygenin/TGR5/Intestinal fibrosis/PERK-eIF2α-Ca2+pathway

Key words

Ulcerative colitis/Phillygenin/TGR5/Intestinal fibrosis/PERK-eIF2α-Ca2+pathway

引用本文复制引用

Huanhuan Xue,Peijie Li,Jing Guo,Tinggui Chen,Shifei Li,Liwei Zhang..Phillygenin ameliorates tight junction proteins reduction,fibrosis,and apoptosis in mice with chronic colitis via TGR5-mediated PERK-eIF2α-Ca2+pathway[J].药物分析学报（英文）,2025,15(1):172-188,17.

基金项目

This research was supported by the National Natural Science Fund of China(Grant Nos.:31800293 and 32370422)and Project of Standard for TCM(Grant No.:ZYBZH-Y-JIN-34). （Grant Nos.:31800293 and 32370422）

药物分析学报（英文）

ISSN：2095-1779

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