中风与神经疾病杂志2025，Vol.42Issue(4)：316-320,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0063
抗Amphiphysin抗体阳性的僵人综合征1例报告并文献复习
Stiff-person syndrome with positive anti-amphiphysin antibodies:A case report and literature review
李承霞 1刘恺鸣 2李来喜1
作者信息
- 1. 广德市人民医院神经内科,安徽 广德 242200
- 2. 浙江大学医学院附属第二医院神经内科,浙江 杭州 310002
- 折叠
摘要
Abstract
Stiff-person syndrome(SPS)is a rare autoimmune neurological disorder with atypical symptoms and signs,which often leads to missed diagnosis or misdiagnosis,resulting in delayed treatment.This article reports a female patient,aged 72 years,who was diagnosed with SPS,and her symptoms were improved after symptomatic treatment in-cluding intravenous injection of human immunoglobulin,corticosteroids,clonazepam,and baclofen.It is suggested that early diagnosis and timely treatment can improve the quality of life and prognosis of SPS patients with positive anti-amphiphysin antibodies.关键词
僵人综合征/抗Amphiphysin抗体/神经免疫Key words
Stiff-person syndrome/Anti-amphiphysin antibodies/Neuroimmunology分类
临床医学引用本文复制引用
李承霞,刘恺鸣,李来喜..抗Amphiphysin抗体阳性的僵人综合征1例报告并文献复习[J].中风与神经疾病杂志,2025,42(4):316-320,5.
