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Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database

Xuan Li Hian Kee Lee Yao-zuo Yuan Taijun Hang Hai-Wei Shi Hongyuan Chen Minwen Huang Yue-Mei Zhao Wenxin Liu Nan Hu Jie Zhou Zi-Yi Wang Sheng Tang Jian-Bin Pan

药物分析学报（英文）2025，Vol.15Issue(2)：401-410,10.

药物分析学报（英文）2025，Vol.15Issue(2)：401-410,10.DOI:10.1016/j.jpha.2024.101072

Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database

Xuan Li ¹Hian Kee Lee ²Yao-zuo Yuan ³Taijun Hang ⁴Hai-Wei Shi ³Hongyuan Chen ⁵Minwen Huang ³Yue-Mei Zhao ⁶Wenxin Liu ⁷Nan Hu ⁸Jie Zhou ⁹Zi-Yi Wang ⁴Sheng Tang ¹⁰Jian-Bin Pan⁵

作者信息

1. Jiangsu Institute for Food and Drug Control,Nanjing,210019,China||School of Pharmacy,China Pharmaceutical University,Nanjing,211112,China
2. School of Environmental and Chemical Engineering,Jiangsu University of Science and Technology,Zhenjiang,Jiangsu,212003,China||Department of Chemistry,National University of Singapore,Singapore,117543,Singapore
3. Jiangsu Institute for Food and Drug Control,Nanjing,210019,China||National Medical Products Administration Key Laboratory for Impurity Profile of Chemical Drugs,Nanjing 210019,China
4. School of Pharmacy,China Pharmaceutical University,Nanjing,211112,China
5. School of Chemistry and Chemical Engineering,Nanjing University,Nanjing,210046,China
6. Jiangsu Institute for Food and Drug Control,Nanjing,210019,China||School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China
7. Jiangsu Institute for Food and Drug Control,Nanjing,210019,China
8. Agilent Technologies Inc,Beijing,100102,China
9. Jiangsu Zhengda Tianqing Pharmaceutical Group Co.,Ltd.,Lianyungang Jiangsu,222006,China
10. School of Environmental and Chemical Engineering,Jiangsu University of Science and Technology,Zhenjiang,Jiangsu,212003,China
折叠

摘要

关键词

Colistimethate sodium/2D-LC-MS/Profiling/Targeted screening/Component deduction/Database

Key words

Colistimethate sodium/2D-LC-MS/Profiling/Targeted screening/Component deduction/Database

引用本文复制引用

Xuan Li,Hian Kee Lee,Yao-zuo Yuan,Taijun Hang,Hai-Wei Shi,Hongyuan Chen,Minwen Huang,Yue-Mei Zhao,Wenxin Liu,Nan Hu,Jie Zhou,Zi-Yi Wang,Sheng Tang,Jian-Bin Pan..Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database[J].药物分析学报（英文）,2025,15(2):401-410,10.

基金项目

The authors are grateful for the financial support from the Sci-ence Research Program Project for Drug Regulation,Jiangsu Medi-cal Products Administration,China(Grant No.:202207),the National Drug Standards Revision Project,China(Grant No.:2023Y41),the National Natural Science Foundation of China(Grant No.:22276080),and the Foreign Expert Project,China(Grant No.:G2022014096L). （Grant No.:202207）

药物分析学报（英文）

ISSN：2095-1779

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