中国临床医学2025，Vol.32Issue(2)：218-224,7.DOI:10.12025/j.issn.1008-6358.2025.20250094
前庭功能障碍对认知功能的影响
Impact of vestibular dysfunction on cognitive function
摘要
Abstract
Objective To investigate the impact of vestibular dysfunction on various domains of cognitive function,providing a basis for developing comprehensive vestibular-cognitive intervention strategies.Methods A total of 33 patients with confirmed unilateral vestibular dysfunction treated at Eye&ENT Hospital,Fudan University between June 2024 and December 2024.Vestibular function was assessed using vestibular evoked myogenic potential(VEMP),caloric testing,video head impulse test(vHIT),and sensory organization test(SOT).Cognitive function was evaluated using mini-mental state examination(MMSE),Montreal cognitive assessment(MoCA),Stroop color-word test,trail making test(TMT),and auditory verbal learning test(AVLT).Subjective symptoms were assessed using dizziness handicap inventory(DHI).Results In the vestibular function assessment of patients,abnormalities in caloric testing,utricle VEMP and saccule VEMP results were most common,with rates of 87.9%,57.6%,and 66.7%,respectively;SOT abnormality primarily characterized by impaired vestibular function(21.2%).Spearman correlation analysis showed age,years of education,hearing ability,and emotional state were associated with overall or specific domains of cognitive function in patients.Greater vestibular dysfunction severity was associated with longer TMT-A time(r=0.443,P=0.010),most severe damage of short-term(r=-0.405,P=0.019)and long-term delayed recalls(r=-0.537,P=0.001).Patients with 31-60 of DHI scores showed longer TMT-A time than patients with 0-30 of DHI scores(P=0.033).Conclusions Patients with vestibular dysfunction exhibit significant impairment in low-frequency semicircular canal and utricle function,which affects attention allocation,information processing speed,and memory performance in cognitive tasks.关键词
前庭功能障碍/认知功能/眩晕/记忆Key words
vestibular dysfunction/cognitive function/vertigo/memory分类
医药卫生引用本文复制引用
张睿琦,赵艳丽,张冬梅,李文妍,吴沛霞..前庭功能障碍对认知功能的影响[J].中国临床医学,2025,32(2):218-224,7.基金项目
国家重点研发计划(2023YFC2508000),复旦大学-复星护理科研基金(FNF202445).Supported by National Key R&D Program of China(2023YFC2508000),Fudan University-Fosun Nursing Research Fund(FNF202445). （2023YFC2508000）
