中国临床药学杂志2025，Vol.34Issue(3)：180-186,7.DOI:10.19577/j.1007-4406.2025.03.004
神经外科重症患者肠内营养制剂临床应用情况
Analysis of clinical application of enteral nutrition formulations in critically ill neurosurgical patients
黄燕勤 1余靓平 1刘忠 2孙瑾 2陈莉2
作者信息
- 1. 厦门大学附属中山医院药学部,厦门 361004
- 2. 厦门大学附属中山医院神经外科,厦门 361004
- 折叠
摘要
Abstract
AIM To investigate the use of enteral nutrition(EN)formulations in patients admitted to a hospital's neurosurgical intensive care unit(ICU),establish evaluation criteria for the rational use of EN formulations,and provide a basis for developing pharmacological intervention protocols.METHODS A total of 136 severe neurosurgical cases using EN preparations were collected from January 2022 to December 2022.The relevant information on nutritional support treatment within 7 days of the cases'admission to the intensive care unit was gathered,and the rationality and safety of EN preparations were analyzed.RESULTS A total of 136 patients included had indications for EN.However,16 cases(11.76％)had inappropriate timing for EN initiation,19 cases(13.97％)had inappropriate drug selection,13 cases(9.56％)had drug interaction issues,and 100 cases(73.53％)had inappropriate dosing.Regarding safety,40 cases(29.41％)experienced diarrhea associated with EN,and no feeding tube blockage events occurred.CONCLUSION The key issues identified in the application of EN formulations for critically ill neurosurgical patients include inappropriate timing of EN initiation,suboptimal formula selection,inadequate dosing regimens,and insufficient consideration of drug-nutrient interactions.These findings provide an evidence base for implementing pharmacy interventions to enhance rational drug use.关键词
神经外科/重症患者/肠内营养制剂/合理性Key words
neurosurgery/critically ill patients/enteral nutrition formula/rationality分类
药学引用本文复制引用
黄燕勤,余靓平,刘忠,孙瑾,陈莉..神经外科重症患者肠内营养制剂临床应用情况[J].中国临床药学杂志,2025,34(3):180-186,7.
