中国美容医学2025，Vol.34Issue(5)：101-104,4.
调Q532nm激光及超脉冲点阵CO2激光联合重组人干扰素α-1b治疗脂溢性角化病疗效观察
Efficacy of Q-switched 532 nm Laser and Ultra-pulsed Fractional CO2 Laser Combined with Recombinant Human Interferon α-1b in the Treatment of Seborrheic Keratosis
靳艳茹 1刘孝兵 1李锋 1谢贤瑞 1王琳2
作者信息
- 1. 安康市中心医院皮肤科 陕西 安康 725000
- 2. 商洛市中心医院皮肤科 陕西 商洛 726000
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of Q-switched 532 nm laser and ultra-pulsed fractional CO2 laser combined with recombinant human interferon α-1b in the treatment of seborrheic keratosis(SK).Methods 120 patients with SK in the hospital were selected from January 2021 to June 2023,and were divided into treatment group(n=60)and control group(n=60)by the random envelope method.The control group was treated with Q-switched 532 nm laser and ultra-pulsed CO2 laser,while the treatment group was added with recombinant human interferon α-1b on the basis of the control group.The clinical efficacy,postoperative recovery status,skin status and occurrence of adverse reactions were compared between both groups.Results After treatment,the total effective rate in treatment group(96.67%)was higher than that in control group(86.67%)(P＜0.05).The natural shedding time of scab,disappearance time of erythema and disappearance time of uneven skin color in treatment group were shorter than those in control group(P＜0.05).There were no significant differences in pain scores at different time points and incidence rates of adverse reactions between groups of patients(P＞0.05).Conclusion The combination of recombinant human interferon α-1 on the basis of Q-switched 532 nm laser and ultra-pulsed fractional CO2 laser does not have adverse influence on patients with SK,and can promote the recovery of patients to a certain extent.关键词
调Q532 nm激光/超脉冲点阵CO2激光/重组人干扰素α-1b/脂溢性角化病Key words
Q-switched 532 nm laser/ultra-pulsed fractional CO2 laser/recombinant human interferon α-1b/seborrheic keratosis分类
临床医学引用本文复制引用
靳艳茹,刘孝兵,李锋,谢贤瑞,王琳..调Q532nm激光及超脉冲点阵CO2激光联合重组人干扰素α-1b治疗脂溢性角化病疗效观察[J].中国美容医学,2025,34(5):101-104,4.
