临床医学工程2025，Vol.32Issue(4)：374-377,4.DOI:10.3969/j.issn.1674-4659.2025.04.0374
CT平扫与CT动态增强扫描对孤立性肺结节良恶性的鉴别诊断价值
The Differential Diagnostic Value of CT Plain Scan and CT Dynamic En-hanced Scan for Benign and Malignant Solitary Pulmonary Nodules
摘要
Abstract
Objective To compare and analyze the differential diagnostic value of CT plain scan and CT dynamic enhanced scan for benign and malignant solitary pulmonary nodules(SPN).Methods A total of 100 patients with SPN who were treated in the CT room of Shangqiu Fourth People's Hospital from January 2021 to December 2024 were selected as the research objects.All patients underwent CT plain scan and CT dynamic enhanced scan.Taking pathological examination results as the gold standard to evaluate the differential diagnosis value of CT plain scan and CT dynamic enhanced scan for benign and malignant SPN.Results The pathological examination results showed that among 100 SPN patients,there were 62 benign cases and 38 malignant cases.No significant difference was found in the detection rate of SPN vacuole sign,ground glass sign,spinous process sign,lobulation sign and pleural depression between CT plain scan and CT dynamic enhanced scan(P＞0.05),while the detection rate of burr and vascular cluster in CT plain scan was lower than that in CT dynamic enhanced scan,with statistically significant difference(P＜0.05).Taking pathological examination results as the golden standard,CT plain scan showed that there were 51 cases with malignant nodules,49 cases with benign nodules,18 cases with misdiagnosis and 5 cases with missed diagnosis,while CT dynamic enhanced scan showed that there were 50 cases with malignant nodules,50 cases with benign nodules,14 cases with misdiagnosis and 2 cases with missed diagnosis.The Kappa value of consistency between CT plain scan diagnosis and pathological examination results was 0.542,and the Kappa value of consistency between CT dynamic enhanced scan diagnosis and pathological examination results was 0.680.No significant difference was found in sensitivity(94.74％vs.86.94％),specificity(77.42％vs.70.97％),accuracy(84.00％vs.77.00％),positive predictive value(72.00％vs.64.71％)and negative predictive value(96.00％vs.89.80％)between CT dynamic enhanced scan and CT plain scan(P＞0.05).The CT dynamic enhanced scan parameters BF,BV,MTT and PS in benign nodules were lower than those in malignant nodules,with statistically significant difference(P＜0.05).Conclusions CT dynamic enhanced scan can analyze the blood supply on the basis of CT plain scan,combined with a variety of imaging signs and functional parameters(BF,BV,MTT and PS),which is helpful to judge the benign and malignant SPN more accurately in clinic.关键词
孤立性肺结节/CT平扫/CT动态增强扫描Key words
Solitary pulmonary nodule/CT plain scan/CT dynamic enhanced scan分类
医药卫生引用本文复制引用
刘艳华,高鹏..CT平扫与CT动态增强扫描对孤立性肺结节良恶性的鉴别诊断价值[J].临床医学工程,2025,32(4):374-377,4.基金项目
河南省二〇二三年科技发展计划项目(项目编号:232102310108) （项目编号:232102310108）
